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CIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo
ArticleAbstract: Protein Kinase CK2 is a serine-threonine kinase frequently deregulated in many human tumors. Here, wPalabras claves:apoptosis, Cancer targeted therapy, Casein kinase 2Autores:Acevedo B.E., Alonso D.F., Ariosa J., Bacardí D.M., Baladron I., Besada-Pérez V., Betancourt L., Castellanos L.R., Cosme K., Cruz M., Díaz A., Falcón-Cama V., Farina H., Garay H.E., Gil J., Gómez D., Gómez R., González L.J., Hernández I., Herrera L., López C., López-Mola E., López-Saura P.A., Marcelo J.L., Mendoza O., Perea-Rodríguez S.E., Perera Y., Puchades Y., Reyes O., Rodriguez A., Sánchez A., Santana A., Serrano J.M., Sigman H., Silva R., Solares M., Thelvia I. Ramos Gómez, Valenzuela-Silva C.M.Fuentes:googlescopusIntramyocardial gene transfer of vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart
ArticleAbstract: Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen that is angiogenicPalabras claves:Collateral development, Coronary artery disease, Gene therapy, Naked plasmid DNA, revascularization, Therapeutic angiogenesisAutores:Alí A., Batista J.F., Chaos N., Coca M., Dominguez H., Garcia-Osuna T., González N., González R., Guevara L., Herrera L., Montequín J.F., Ojalvo A.G., Perera A., Puchades Y., Quián Y.P., Reima C., Reyes J.L., Santiago Nelson Vispo, Seralena A., Silva R., Vazquez R.Fuentes:scopusSafety and preliminary efficacy data of a novel Casein Kinase 2 (CK2) peptide inhibitor administered intralesionally at four dose levels in patients with cervical malignancies
ArticleAbstract: Background: Cervical cancer is now considered the second leading cause of death among women worldwidPalabras claves:Autores:Acevedo B.E., Alonso D.F., Baladron I., Castillo D., Díaz A., Gómez R., González C.A., Herrera L., López-Saura P.A., Perea-Rodríguez S.E., Santana A., Sigman H., Solares A.M., Thelvia I. Ramos Gómez, Valenzuela-Silva C.M.Fuentes:googlescopusTherapeutic angiogenesis following intramuscular gene transfer of vascularendothelial growth factor 121 in a dog model of hindlimb ischemia
ArticleAbstract: Vascular endothelial growth factor (VEGF), an endothelial cell-specific mitogen, has been shown to pPalabras claves:Collateral development, Gene therapy, Naked plasmid DNA, Peripheral vascular disease, revascularizationAutores:Aldama A., Alfonso M.A., Alí A., Herrera L., López-Saura P.A., Montequín J.F., Ojalvo A.G., Puchades Y., Santiago Nelson Vispo, Seralena A., Seuc A., Silva R., Simón R., Sorell L.T., Vazquez R.Fuentes:scopus