Expression and folding of an interleukin-2-proinsulin fusion protein and its conversion into insulin by a single step enzymatic removal of the C-peptide and the N-terminal fused sequence

Article

Abstract: We report the expression in E. coli of a proinsulin fusion protein carrying a modified interleukin-2

Palabras claves:

Enzymatic processing, Proinsulin folding, Recombinant insulin

Autores:

Besada-Pérez V., Castellanos‐Serra L., Eugenio Hardy, Falcón-Cama V., Fernandez C., Gonzalez M., Herrera L., Perez G., Santiago Nelson Vispo, Santos-Savio A., Silva A., Ubieta R.

Fuentes:

scopus