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Combining solid phase synthesis and chromatographic purification for efficient peptide manufacture
ArticleAbstract: In recent years, peptides have gained an important position in the drug arena for a variety of treatPalabras claves:Oligos-peptides, Peptide purification, Peptide synthesis, Polystyrene resins, Solid phase peptide synthesisAutores:Alberício F., B. G. De la Torre, Basso A., Musaimi O.A.L., Serban S., Summers B.D.Fuentes:scopusAnalytical methodologies to assure successful peptide synthesis when utilizing polystyrene/DVB resins
ArticleAbstract: Solid-phase peptide synthesis has become an important technique as the method of choice to deliver hPalabras claves:Fluorenylmethoxycarbonyl (Fmoc), Functionalization, MORPHOLOGY, Peer Reviewed, Polystyrene resins, Solid support, Solid-phase peptide synthesis, swellingAutores:Al Musaimi O., Alberício F., Alhassan M., B. G. De la Torre, Basso A., Serban S., Summers B.D.Fuentes:scopusCalculating Resin Functionalization in Solid-Phase Peptide Synthesis Using a Standardized Method based on Fmoc Determination
ArticleAbstract: Solid-phase synthesis is the method of choice for peptide preparation in both research and industriaPalabras claves:Fmoc, resin functionalization, solid-phase synthesis, standardizationAutores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A.Fuentes:scopusGreening the Solid-Phase Peptide Synthesis Process. 2-MeTHF for the Incorporation of the First Amino Acid and Precipitation of Peptides after Global Deprotection
ArticleAbstract: In solid-phase peptide synthesis, dichloromethane is the predominant solvent used to incorporate thePalabras claves:2-MeTHF, Dipeptide formation, incorporation, precipitation, Racemization, Solid-phase peptide synthesisAutores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A., Collins J.M., El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusInvestigating green ethers for the precipitation of peptides after global deprotection in solid-phase peptide synthesis
ReviewAbstract: Diethyl ether and methyl tert-butyl ether are the solvents most widely used for peptide precipitatioPalabras claves:Autores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A., Collins J.M., Jad Y.E., Kumar A.Fuentes:scopusγ-Valerolactone (GVL): An eco-friendly anchoring solvent for solid-phase peptide synthesis
ArticleAbstract: Due to the hazardous nature of CH2Cl2, regulatory authorities have imposed restrictions to minimizePalabras claves:Dipeptide formation, Green Chemistry, Racemization, Wang resinAutores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A., El-Faham A.Fuentes:scopus