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Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators
ArticleAbstract: The immune system is highly diverse, but characterization of its genetic architecture has lagged behPalabras claves:adaptive immune system, association, autoimmunity, Genetics, Genome-wide association, immune phenotype, susceptibilityAutores:Boeckxstaens G., Bowness P., Chen L., Dooley J., Dubois B., Goris A., Hilven K., Humblet-Baron S., Josselyn E. Garcia-Perez, Lagou V., Liston A., Mallants K., Moisse M., Prezzemolo T., Smets I., Van Damme P., Van Horebeek L., Vandebergh M.Fuentes:scopusMultiple sclerosis risk variants alter expression of co-stimulatory genes in B cells
ArticleAbstract: The increasing evidence supporting a role for B cells in the pathogenesis of multiple sclerosis promPalabras claves:B cells, CD40, CD86, Multiple Sclerosis, susceptibilityAutores:Ban M., Coles A.J., Compston A., Dooley J., Dubois B., Fiddes B., Goris A., He D., Humblet-Baron S., Jones J., Josselyn E. Garcia-Perez, Liao W., Liston A., Mallants K., Sawcer S., Smets I., Wang G.Fuentes:scopus