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scopus(18)
Antiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusAntiapoptotic effects of roscovitine on camptothecin-induced DNA damage in neuroblastoma cells
ArticleAbstract: In the present study dopaminergic neuroblastoma B65 cells were exposed to Camptothecin (CPT) (0.5-10Palabras claves:Ataxia telangiectasia mutated, camptothecin, cell cycle, RoscovitineAutores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Pizarro J.G., Verdaguer E., Zárate C.B.Fuentes:scopusContent and traffic of taurine in hippocampal reactive astrocytes
ArticleAbstract: Taurine is one of the most abundant free amino acids in the mammalian central nervous system, wherePalabras claves:Astrogliosis, Epilepsy, Kainic acid, neuroprotection, Taurine transporterAutores:Aguado F., Antoni Camins, Auladell C., De Lemos M.L., Junyent F., Paco S., Pallás M., Romero R., Utrera J.Fuentes:scopusCalpains as a target for therapy of neurodegenerative diseases: Putative role of lithium
ReviewAbstract: Lithium is a simple cation that has been used clinically since 1950 for the treatment of bipolar disPalabras claves:apoptosis, Calcium homeostasis, Calpain, Cell cycle control, Cytoskeleton, DNA damage, Kinases, Lithium, Neurodegeneration, neurodegenerative diseases, signal transduction, Tau kinasesAutores:Antoni Camins, Canudas A.M., Crespo-Biel N., Junyent F., Pallás M., Verdaguer E.Fuentes:scopusAging biology: A new frontier for drug discovery
ReviewAbstract: Introduction: The prevalence of age-related pathologies, such as cardiovascular disease, neurodegenePalabras claves:Autores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopusGSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons
ArticleAbstract: In the present study, we evaluated the effects of roscovitine (Rosco) and flavopiridol (Flavo), bothPalabras claves:apoptosis, Cerebellar granular cells, flavopiridol, GSK3β, RoscovitineAutores:Antoni Camins, Auladell C., de la Torre A.V., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusGene expression profile in JNK3 null mice: A novel specific activation of the PI3K/AKT pathway
ArticleAbstract: JNK3 is mainly expressed in the CNS and it plays a crucial role in neuronal death in several neurodePalabras claves:Akt, Gene profiling, JNK, Neurodegeneration, neuroprotection, PI3KAutores:Antoni Camins, Auladell C., De Lemos M.L., Ferrer I., Folch J., Junyent F., Ortuo-Sahagún D., Pallás M., Romero R., Verdaguer E., Zárate C.B.Fuentes:scopusErratum: Differences in activation of ERK1/2 and p38 kinase in Jnk3 null mice following KA treatment (Journal of Neurochemistry (2010) 114 (1315-1322))
OtherAbstract:Palabras claves:Autores:Antoni Camins, Auladell C., De Lemos M.L., Ferrer I., Folch J., Junyent F., Pallás M., Romero R., Verdaguer E.Fuentes:scopusStudy of the pathways involved in apoptosis induced by PI3K inhibition in cerebellar granule neurons
ArticleAbstract: In the present study we focused in the PI3K/Akt pathway which plays a key role in neuronal survival.Palabras claves:BrdU, Caspase-6, Cdk5/p25, cell cycle, LY294002Autores:Antoni Camins, Auladell C., Folch J., Junyent F., Palls M., Pelegrí Gabalda C., Torre A.V.D.L., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusNeuroprotective Effects of the Absence of JNK1 or JNK3 Isoforms on Kainic Acid-Induced Temporal Lobe Epilepsy-Like Symptoms
ArticleAbstract: The activation of c-Jun-N-terminal kinases (JNK) pathway has been largely associated with the pathogPalabras claves:c-Jun N-terminal kinase, Excitotoxicity, hippocampus, inflammation, Kainic acid, Knockout mice, Neurodegeneration, neuroprotectionAutores:Antoni Camins, Auladell C., Castro-Torres R.D., De Lemos M.L., Folch J., Junyent F., Olloquequi J., Verdaguer E., Zárate C.B.Fuentes:scopus