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Journal of Pineal Research(5)
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Chronic administration of melatonin reduces cerebral injury biomarkers in SAMP8
ArticleAbstract: Certain effects of melatonin on senescence were investigated. The experimental model used was 10-monPalabras claves:aging, ck5/p35, GSK3β, Oxidative Stress, SAMP8, TauAutores:Antoni Camins, Caballero B., Canudas A.M., Coto-Montes A., Gutiérrez-Cuesta J., Pallás M., Romeu M., Sureda F.X.Fuentes:scopusFavorable effects of a prolonged treatment with melatonin on the level of oxidative damage and neurodegeneration in senescence-accelerated mice
ArticleAbstract: Senescence-accelerated mice (SAMP8) and senescence-accelerated resistant mice (SAMR1) were studied aPalabras claves:aging, BRAIN, Melatonin receptor-1, Neurofibrillary tangle, Nuclear factor-kappa B, Retinoic acid receptor-related orphan receptor-α1, Senescence-accelerated miceAutores:Antoni Camins, Caballero B., Coto-Montes A., Gonzalo-Calvo D.D., Gutiérrez-Cuesta J., Huidobro-Fernández C., Pallás M., Rodríguez-Colunga M.J., Sierra V., Soria-Valles C., Tolivia D., Vega-Naredo I.Fuentes:scopusElevated oxidative stress in the brain of senescence-accelerated mice at 5 months of age
ArticleAbstract: The senescence-accelerated mouse (SAM) is a useful animal model to study aging or age-associated disPalabras claves:aging, Alpha-synuclein, Antioxidant defence, Brain damage, Gliosis, Oxidative Stress, Senescence-accelerated model mouse (SAM), Tau phosphorylationAutores:Álvarez-García O., Antoni Camins, Caballero B., Coto-Montes A., García J., Pallás M., Sierra V., Tomás-Zapico C., Vega-Naredo I.Fuentes:scopusEvaluation of potential pro-survival pathways regulated by melatonin in a murine senescence model
ArticleAbstract: We examined the effect of melatonin on pro-survival processes in three groups of mice. Untreated senPalabras claves:aging, Amyloid β, BRAIN, Cysteine proteases, Sirt1Autores:Antoni Camins, Coto-Montes A., Gutiérrez-Cuesta J., Jiménez A., Pallás M., Tajes M.Fuentes:scopusDysfunction of astrocytes in senescence-accelerated mice SAMP8 reduces their neuroprotective capacity
ArticleAbstract: Early onset increases in oxidative stress and tau pathology are present in the brain of senescence-aPalabras claves:astrocytes, Glutamate uptake, neuroprotection, Oxidative Stress, Senescence-accelerated mice, Tau proteinAutores:Antoni Camins, Coto-Montes A., Cristòfol R., Díez-Vives C., García-Matas S., Gutiérrez-Cuesta J., Pallás M., Rubio-Acero R., Sanfeliu C.Fuentes:scopusNeurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol
ArticleAbstract: The senescence-accelerated prone 8 (SAMP8) mouse strain shows early cognitive loss that mimics the dPalabras claves:aging brain, melatonin, Mitochondria, Resveratrol, SAMP8 mouse neuron cultures, Sirtuin 1Autores:Antoni Camins, Corpas R., Coto-Montes A., Cristòfol R., Pallás M., Porquet D., Sanfeliu C., Serret J.Fuentes:scopusMelatonin alters cell death processes in response to age-related oxidative stress in the brain of senescence-accelerated mice
ArticleAbstract: We studied the effect of age and melatonin on cell death processes in brain aging. Senescence-accelePalabras claves:aging, apoptosis, Autophagy, Calpains, Caspases, Cathepsins, melatoninAutores:Antoni Camins, Caballero B., Coto-Montes A., Gonzalo-Calvo D.D., Huidobro-Fernández C., Pallás M., Rodríguez-Colunga M.J., Sierra V., Soria-Valles C., Tolivia D., Vega-Naredo I.Fuentes:scopusLong-term physical exercise induces changes in sirtuin 1 pathway and oxidative parameters in adult rat tissues
ArticleAbstract: The protein deacetylase, sirtuin 1, is suggested as a master regulator of exercise-induced beneficiaPalabras claves:AMPK, heart, Liver, Mitochondrial biogenesis, Muscle, Oxidative Stress, PGC-1α, Sirtuin 1, TreadmillAutores:Antoni Camins, Bayod S., Canudas A.M., Coto-Montes A., de Luxán-Delgado B., Del Valle J., Escorihuela R.M., Lalanza J.F., Pallás M., Sanchez-Roige S.Fuentes:scopusResveratrol and neurodegenerative diseases: Activation of SIRT1 as the potential pathway towards neuroprotection
ReviewAbstract: One of the current problems in medicine research is the development of safe drugs for the treatmentPalabras claves:Autores:Antoni Camins, Casadesús G., Coto-Montes A., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.Fuentes:scopus