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scopus(31)
Characterization of the A<inf>2A</inf>R-D<inf>2</inf>R interface: Focus on the role of the C-terminal tail and the transmembrane helices
ArticleAbstract: A single serine point mutation (S374A) in the adenosine A2A receptor (A2AR) C-terminal tail reducesPalabras claves:Adenosine A receptor 2A, Dopamine D receptor 2, G protein coupled receptors, Heteromerization, Protein-protein interaction, Transmembrane segmentsAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Corrales F., Flajolet M., Frankowska M., Fuxe K., Gómez-Soler M., Heintz N., Marcellino D., Narváez M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusAgonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family
ArticleAbstract: Fibroblast growth factor receptor 1 (FGFR1) is known to be activated by homodimerization in the presPalabras claves:BRET, FGFR1, Fibroblast growth factors, Homodimerization, MAPKAutores:Agnati L.F., Belluardo N., Borroto-Escuela D.O., Ciruela F., Fuxe K., Mudó G., Narváez M., Pérez-Alea M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusG protein-coupled receptor heterodimerization in the Brain
Book PartAbstract: G protein-coupled receptors (GPCRs) play critical roles in cellular processes and signaling and havePalabras claves:allosteric modulation, Depression, Fibroblast growth factor receptor, neuronal plasticity, Receptor heterocomplex, serotonin receptorsAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Fuxe K., Garriga P., Narváez M., Palkovits M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusG-protein-coupled receptors oligomerization: Emerging signaling units and new opportunities for drug design
ArticleAbstract: G-protein-coupled receptors (GPCRs) are a widespread family of transmembrane receptors with differenPalabras claves:Dimers, disease, drug design, G-protein-coupled receptors, ligand, OligomerizationAutores:Borroto-Escuela D.O., Fuxe K., Garriga P., Ramon E., Rivera D., Tena-Campos M., W. Romero-FernandezFuentes:scopusGPCR heteromers and their allosteric receptor-receptor interactions
ArticleAbstract: The concept of intramembrane receptor-receptor interactions and evidence for their existences were iPalabras claves:Adenosine receptor, allosteric modulation, Dopamine receptors, GPCR, moonlighting, Oligomers, Receptor G protein coupling, Receptor interface, Receptor mosaic, Receptor recognition, Receptor signaling, Receptor trafficking, Triplet homologiesAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Ferraro L., Filip M., Frankowska M., Fuxe K., Guidolin D., Marcellino D., Tanganelli S., Tarakanov A.O., W. Romero-Fernandez, Woods A.S.Fuentes:scopusExtrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks
ArticleAbstract: Extrasynaptic neurotransmission is an important short distance form of volume transmission (VT) andPalabras claves:Extrasynaptic, G protein coupled receptors, Heteromers, Neurotransmission, Receptor-receptor interactions, Striatal networks, Volume transmission, Wiring transissionAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Díaz-Cabiale Z., Ferraro L., Fuxe K., Garriga P., Guescini M., Narvaez J.A., Rivera A., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusFibroblast growth factor receptor 1 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity
ArticleAbstract: Background: The hippocampus and its 5-hydroxytryptamine transmission plays an important role in deprPalabras claves:allosteric modulation, Depression, Fibroblast growth factor receptor, Heteroreceptor, neuronal plasticity, serotonin receptorsAutores:Agnati L.F., Belluardo N., Borroto-Escuela D.O., Ciruela F., Di Liberto V., Fuxe K., Mudó G., Narváez M., Pérez-Alea M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusEvidence for the existence of dopamine d2-oxytocin receptor heteromers in the ventral and dorsal striatum with facilitatory receptor-receptor interactions
OtherAbstract:Palabras claves:Autores:Agnati L.F., Borroto-Escuela D.O., Fuxe K., W. Romero-FernandezFuentes:scopusDissecting the conserved NPxxY motif of the M <inf>3</inf> muscarinic acetylcholine receptor: Critical role of Asp-7.49 for receptor signaling and multiprotein complex formation
ArticleAbstract: Acetylcholine challenge produces M 3 muscarinic acetylcholine receptor activation and accessory/scafPalabras claves:Desensitization, G protein-coupled receptors, Monomeric small G proteins, Muscarinic acetylcholine receptors, NPxxY motif, Phospholipase C, Phospholipase DAutores:Borroto-Escuela D.O., Ciruela F., Correia P.A., Fuxe K., García-Negredo G., Garriga P., W. Romero-FernandezFuentes:scopusDiversity and bias through receptor-receptor interactions in GPCR heteroreceptor complexes. Focus on examples from dopamine D2 receptor heteromerization
ReviewAbstract: Allosteric receptor-receptor interactions in GPCR heteromers appeared to introduce an intermolecularPalabras claves:allosteric modulation, Biased recognition, Biased signaling, G protein-coupled receptor, Heterodimerization, Receptor diversity, Receptor heterodimers, Receptor-receptor interactionsAutores:Agnati L.F., Borroto-Escuela D.O., Díaz-Cabiale Z., Ferraro L., Filip M., Fuxe K., Garriga P., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopus