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G protein-coupled receptor heterodimerization in the Brain
Book PartAbstract: G protein-coupled receptors (GPCRs) play critical roles in cellular processes and signaling and havePalabras claves:allosteric modulation, Depression, Fibroblast growth factor receptor, neuronal plasticity, Receptor heterocomplex, serotonin receptorsAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Fuxe K., Garriga P., Narváez M., Palkovits M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusExtrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks
ArticleAbstract: Extrasynaptic neurotransmission is an important short distance form of volume transmission (VT) andPalabras claves:Extrasynaptic, G protein coupled receptors, Heteromers, Neurotransmission, Receptor-receptor interactions, Striatal networks, Volume transmission, Wiring transissionAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Díaz-Cabiale Z., Ferraro L., Fuxe K., Garriga P., Guescini M., Narvaez J.A., Rivera A., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusFibroblast growth factor receptor 1 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity
ArticleAbstract: Background: The hippocampus and its 5-hydroxytryptamine transmission plays an important role in deprPalabras claves:allosteric modulation, Depression, Fibroblast growth factor receptor, Heteroreceptor, neuronal plasticity, serotonin receptorsAutores:Agnati L.F., Belluardo N., Borroto-Escuela D.O., Ciruela F., Di Liberto V., Fuxe K., Mudó G., Narváez M., Pérez-Alea M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusDopamine D1 and D2 receptor immunoreactivities in the arcuate-median eminence complex and their link to the tubero-infundibular dopamine neurons
ArticleAbstract: Dopamine D1 and D2 receptor immunohistochemistry and Golgi techniques were used to study the structuPalabras claves:Arcuate-median eminence complex, Dopamine D1 and D2 receptors, Dopamine receptor colocalization, Luteinizing hormone releasing hormone, Tubero-infundibular dopamine neurons, Volume transmissionAutores:Agnati L.F., Borroto-Escuela D.O., Di Palma M., Fuxe K., Larriva Sahd J., Narváez M., Vargas-Barroso V., W. Romero-FernandezFuentes:scopusMoonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field
ReviewAbstract: There is serious interest in understanding the dynamics of the receptor-receptor and receptor-proteiPalabras claves:G protein-coupled receptors, Heterodimerization, moonlighting, neuropsychiatric disorders, neurotherapeutic targets, receptorreceptor interactionsAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Fuxe K., Palkovits M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusHallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes
ArticleAbstract: Dopamine D2LR-serotonin 5-HT2AR heteromers were demonstrated in HEK293 cells after cotransfection ofPalabras claves:2,5-Dimethoxy-4-iodoamphetamine, allosteric modulation, Antipsychotic drugs, dopamine D2 receptor, G-protein-coupled receptors, Heterodimerization, Heteroreceptor complexes, Lysergic acid diethylamide, Receptor-receptor interactions, Serotonin 5-HT2A receptorAutores:Agnati L.F., Borroto-Escuela D.O., Fuxe K., Narváez M., Oflijan J., W. Romero-FernandezFuentes:scopusOn the G-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: Focus on their role in pain modulation
ArticleAbstract: The modulatory role of allosteric receptor-receptor interactions in the pain pathways of the CentralPalabras claves:Autores:Agnati L.F., Borroto-Escuela D.O., Fuxe K., Rivera A., Tarakanov A.O., Van Craenenbroeck K., W. Romero-FernandezFuentes:scopusOn the role of volume transmission and receptor-receptor interactions in social behaviour: Focus on central catecholamine and oxytocin neurons
ArticleAbstract: This article is focused on understanding the mechanisms for the interactions between the central catPalabras claves:Alpha2a adrenoceptor, Anti-stress, D2, dopamine, Food intake, Heteromer, Nucleus accumbens, oxytocin, Oxytocin receptor, pair bonding, Social attachment, Vasopressin, Volume transmissionAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Díaz-Cabiale Z., Fuxe K., Leo G., Manger P., W. Romero-FernandezFuentes:scopusUnderstanding the balance and integration of volume and synaptic transmission. Relevance for psychiatry
ReviewAbstract: The major difference of synaptic transmission vs volume transmission (VT) is about the channels whicPalabras claves:G protein coupled receptors, neuroinflammation, Receptor-receptor interactions, Schizophrenia, Toxoplasma gondii, Volume transmissionAutores:Agnati L.F., Borroto-Escuela D.O., Cullheim S., Díaz-Cabiale Z., Ferraro L., Filip M., Fuxe K., Guidolin D., Manger P., Perez de la Mora M., Rivera A., Skieterska K., Tanganelli S., Tarakanov A.O., Van Craenenbroeck K., W. Romero-FernandezFuentes:scopusVolume transmission and its different forms in the central nervous system
ArticleAbstract: Volume transmission (VT) is a widespread mode of intercellular communication that occurs in the extrPalabras claves:Chinese medicine, extrasynaptic volume transmission, long distance volume transmission, Meridian, Roamer type of volume transmissionAutores:Agnati L.F., Borroto-Escuela D.O., Fuxe K., W. Romero-Fernandez, Zhang W.B.Fuentes:scopus