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Brain apoptosis and carotid artery reactivity in fetal asphyctic preconditioning
ArticleAbstract: We aimed to develop a model of fetal hypoxia-ischemia (HI) preconditioning that reflects the pathophPalabras claves:apoptosis, Carotid reactivity, Fetal asphyxia, Perinatal asphyxia, preconditioningAutores:Antonio Wenceslao Danilo Gavilanes, Blanco C.E., Steinbusch H., Steinbusch H.W.M., Strackx E., van den Hove D.L.A., Villamor E., Vles J.S.H., Zoer B.Fuentes:scopusA combined behavioral and morphological study on the effects of fetal asphyxia on the nigrostriatal dopaminergic system in adult rats
ArticleAbstract: Fetal asphyxic insults in the brain are known to be associated with developmental neurological problPalabras claves:dopamine, Fetal asphyxia, Glial fibrillary acidic protein (GFAP), locomotion, Open field, RAT, Striatum, Substantia nigra, Tyrosine hydroxylase (TH), VentriculomegalyAutores:Antonio Wenceslao Danilo Gavilanes, Blanco C.E., Steinbusch H., Steinbusch H.W.M., Strackx E., van den Hove D.L.A., Vles J.S.H.Fuentes:scopusCerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep
ArticleAbstract: Background: Hypoxic-ischemic encephalopathy (HIE) is one of the most important causes of brain injurPalabras claves:hypoxic-ischemic encephalopathy, inflammation, Microglia, neutrophils, Oligodendrocytes, Preterm, spleenAutores:Andriessen P., Antonio Wenceslao Danilo Gavilanes, Cleutjens J.P.M., Collins J.J.P., De Munter S., Germeraad W.T.V., Jellema R.K., Jennekens W., Kramer B.W., Kuypers E., Lima Passos V., Ophelders D.R.M.G., Seehase M., Steinbusch H.W.M., Vanderlocht J., Vles H.J.S., Wolfs T.G.A.M., Zwanenburg A.Fuentes:scopusApoptosis in the rat spinal cord during postnatal development; the effect of perinatal asphyxia on programmed cell death
ArticleAbstract: The aim of our study was to investigate the effect of perinatal asphyxia on developmental apoptosisPalabras claves:ED1, O4, TUNELAutores:Antonio Wenceslao Danilo Gavilanes, Blanco C.E., De Louw A., De Vente J., Steinbusch H., Steinbusch H.W.M., Troost J., Vles J.S.H.Fuentes:scopusFetal asphyxia leads to the loss of striatal presynaptic boutons in adult rats
ArticleAbstract: Fetal asphyxic insults in the brain are known to be associated with developmental and neurological pPalabras claves:aging, Fetal asphyxia, Neurodegenerative disorders, Synapse, synaptophysinAutores:Antonio Wenceslao Danilo Gavilanes, Blanco C.E., Steinbusch H., Steinbusch H.W.M., Strackx E., van den Hove D.L.A., Vles J.S.H.Fuentes:scopusNitric Oxide Production in the Striatum and Cerebellum of a Rat Model of Preterm Global Perinatal Asphyxia
ArticleAbstract: Encephalopathy due to perinatal asphyxia (PA) is a major cause of neonatal morbidity and mortality iPalabras claves:asphyxia, cGMP, Neuronal nitric oxide synthase, Nitrosidative stress, Peroxynitrite, Selective vulnerabilityAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Blanco C.E., De Vente J., Steinbusch H.W.M., Van de Berg W.D.J.Fuentes:scopusIncreased number of cerebellar granule cells and astrocytes in the internal granule layer in sheep following prenatal intra-amniotic injection of lipopolysaccharide
ArticleAbstract: Chorioamnionitis is an important problem in perinatology today, leading to brain injury and neurologPalabras claves:astrocytes, Cerebellum, chorioamnionitis, FETAL, Granule cell loss, Intra-amniotic, LPS, stereologyAutores:Antonio Wenceslao Danilo Gavilanes, Gantert M., Garnier Y., Hürter H., Kramer B.W., Lemmens M.A.M., Moers V., Rieke R., Steinbusch H.W.M., Strackx E., Van Kooten I.A.J., Vles J.S.H., Zimmermann L.J.I.Fuentes:scopusPeriaqueductal grey stimulation induced panic-like behaviour is accompanied by deactivation of the deep cerebellar nuclei
ArticleAbstract: Until recently, the cerebellum was primarily considered to be a structure involved in motor behaviouPalabras claves:Cerebellum, Deep brain stimulation, Escape behaviour, Periaqueductal grey, Ventromedial hypothalamusAutores:Antonio Wenceslao Danilo Gavilanes, Ayyildiz M., Hoogland G., Kaplan S., Lim L.W., Moers-Hornikx V.M.P., Steinbusch H.W.M., Temel Y., Vles J.S.H.Fuentes:scopusSystemic multipotent adult progenitor cells improve long-term neurodevelopmental outcomes after preterm hypoxic-ischemic encephalopathy
ArticleAbstract: There is an urgent need for therapies that could reduce the disease burden of preterm hypoxic-ischemPalabras claves:hypoxic-ischemic encephalopathy, Neurodevelopment, Preterm brain, Stem cell therapyAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Kramer B.W., Mays R.W., Paes D., Peter A. Chedraui, Robertson N.J., Steinbusch H.W.M., Vaes B., van den Hove D.L.A., van Mechelen R., Vermeer M.Fuentes:scopusThe influence of anesthetics on substantia nigra tyrosine hydroxylase expression and tau phosphorylation in the hypoxic-ischemic near-term lamb
ArticleAbstract: BackgroundGeneral anesthetics could protect key neurotransmitter systems, such as the dopaminergic sPalabras claves:Autores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Cleutjens J.P.M., Engelbertink I., Gussenhoven R., Jellema R.K., Kramer B.W., Seehase M., Steinbusch H.W.M., Van Dijck F.J.P., van Mechelen R., Zimmermann L.J.I.Fuentes:scopus