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Clinical Implications of Epigenetic Dysregulation in Perinatal Hypoxic-Ischemic Brain Damage
ReviewAbstract: Placental and fetal hypoxia caused by perinatal hypoxic-ischemic events are major causes of stillbirPalabras claves:Biomarker, DNA methylation, histone modifications, Hypoxia, hypoxic-ischemic encephalopathy, ischemia, microRNAsAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Bruno M.A., Bustelo M., Loidl C.F., Steinbusch H.W.M., van den Hove D.L.A.Fuentes:scopusBrain apoptosis and carotid artery reactivity in fetal asphyctic preconditioning
ArticleAbstract: We aimed to develop a model of fetal hypoxia-ischemia (HI) preconditioning that reflects the pathophPalabras claves:apoptosis, Carotid reactivity, Fetal asphyxia, Perinatal asphyxia, preconditioningAutores:Antonio Wenceslao Danilo Gavilanes, Blanco C.E., Steinbusch H., Steinbusch H.W.M., Strackx E., van den Hove D.L.A., Villamor E., Vles J.S.H., Zoer B.Fuentes:scopus25 years of research on global asphyxia in the immature rat brain
ReviewAbstract: Hypoxic-ischemic encephalopathy remains a common cause of brain damage in neonates. Preterm infantsPalabras claves:Encephalopathy, functional outcome, Hypoxic-ischemia, Preterm infant, SubmersionAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Kramer B.W., Steinbusch H.W.M., van den Hove D.L.A., Vles J.S.H.Fuentes:scopusA combined behavioral and morphological study on the effects of fetal asphyxia on the nigrostriatal dopaminergic system in adult rats
ArticleAbstract: Fetal asphyxic insults in the brain are known to be associated with developmental neurological problPalabras claves:dopamine, Fetal asphyxia, Glial fibrillary acidic protein (GFAP), locomotion, Open field, RAT, Striatum, Substantia nigra, Tyrosine hydroxylase (TH), VentriculomegalyAutores:Antonio Wenceslao Danilo Gavilanes, Blanco C.E., Steinbusch H., Steinbusch H.W.M., Strackx E., van den Hove D.L.A., Vles J.S.H.Fuentes:scopusDevelopmental apoptosis in the spinal cord white matter in neonatal rats
ArticleAbstract: We investigated developmental apoptosis in the white matter of the cervical spinal cord at postnatalPalabras claves:Caspase-3, Co-localization, ED-1, O4, Oligodendrocytes, TUNELAutores:Antonio Wenceslao Danilo Gavilanes, Blanco C.E., De Louw A., De Vente J., Steinbusch H., Steinbusch H.W.M., Troost J., Van de Berg W.D.J., Vles J.S.H.Fuentes:scopusFetal asphyctic preconditioning protects against perinatal asphyxia- induced apoptosis and astrogliosis in neonatal brain
ArticleAbstract: Hypoxic-ischemic preconditioning is an endogenous mechanism in which exposure to a sublethal episodePalabras claves:apoptosis, Astrogliosis, Fetal preconditioning, Hypoxia-ischemia, Neonatal brain, Perinatal asphyxiaAutores:Antonio Wenceslao Danilo Gavilanes, Cox-Limpens K.E.M., de Jong M., Steinbusch H.W.M., Strackx E., van den Hove D.L.A., van Ekkendonk J.R.A., Vles J.S.H., Zimmermann L.J.I.Fuentes:scopusFetal asphyxia leads to a decrease in dorsal raphe serotonergic neurons
ArticleAbstract: The aim of the present study was to determine the effects of fetal asphyxia (FA) on anxiety and seroPalabras claves:5-Hydroxytryptamine/serotonin, anxiety, Dorsal raphe nucleus, Fetal asphyxia, Rat brain, agingAutores:Antonio Wenceslao Danilo Gavilanes, Blanco C.E., Prickaerts J., Steinbusch H., Steinbusch H.W.M., Strackx E., van den Hove D.L.A., Vles J.S.H.Fuentes:scopusFetal asphyxia leads to the loss of striatal presynaptic boutons in adult rats
ArticleAbstract: Fetal asphyxic insults in the brain are known to be associated with developmental and neurological pPalabras claves:aging, Fetal asphyxia, Neurodegenerative disorders, Synapse, synaptophysinAutores:Antonio Wenceslao Danilo Gavilanes, Blanco C.E., Steinbusch H., Steinbusch H.W.M., Strackx E., van den Hove D.L.A., Vles J.S.H.Fuentes:scopusNitric Oxide Production in the Striatum and Cerebellum of a Rat Model of Preterm Global Perinatal Asphyxia
ArticleAbstract: Encephalopathy due to perinatal asphyxia (PA) is a major cause of neonatal morbidity and mortality iPalabras claves:asphyxia, cGMP, Neuronal nitric oxide synthase, Nitrosidative stress, Peroxynitrite, Selective vulnerabilityAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Blanco C.E., De Vente J., Steinbusch H.W.M., Van de Berg W.D.J.Fuentes:scopusIncreased number of cerebellar granule cells and astrocytes in the internal granule layer in sheep following prenatal intra-amniotic injection of lipopolysaccharide
ArticleAbstract: Chorioamnionitis is an important problem in perinatology today, leading to brain injury and neurologPalabras claves:astrocytes, Cerebellum, chorioamnionitis, FETAL, Granule cell loss, Intra-amniotic, LPS, stereologyAutores:Antonio Wenceslao Danilo Gavilanes, Gantert M., Garnier Y., Hürter H., Kramer B.W., Lemmens M.A.M., Moers V., Rieke R., Steinbusch H.W.M., Strackx E., Van Kooten I.A.J., Vles J.S.H., Zimmermann L.J.I.Fuentes:scopus