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CD69 is a direct HIF-1α target gene in hypoxia as a mechanism enhancing expression on tumor-infiltrating T lymphocytes
ArticleAbstract: CD69 is an early activation marker on the surface of T lymphocytes undergoing activation by cognatePalabras claves:CD69, HIF-1α, Hypoxia, tumor microenvironment, tumor-infiltrating lymphocytes (TILs)Autores:Aragonés J., Aznar M.Á., Azpilikueta A., Bolaños E., de la Fuente H., Etxeberria I., Garasa S., Labiano S., Maiso P., Manuel Ortiz de Landázuri, Meléndez-Rodríguez F., Melero I., Molina C., Palazón A., Sánchez-Paulete A.R., Sánchez‐Madrid F., Teijeira A.Fuentes:scopusThe HIF-1α hypoxia response in tumor-infi ltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy
ArticleAbstract: The tumor microenvironment of transplanted and spontaneous mouse tumors is profoundly deprived of oxPalabras claves:Autores:Alfaro C., Aragonés J., Hervás-Stubbs S., Jure-Kunkel M., Manuel Ortiz de Landázuri, Martínez-Forero I., Melero I., Morales-Kastresana A., Palazón A., Peñuelas I., Perez-Gracia J.L., Rouzaut A., Sanmamed M.F., Teijeira A.Fuentes:scopus