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A modified variant of human Interleukin-15 as a novel antigen for active immunotherapy in rheumatoid arthritis
ReviewAbstract: Interleukin (IL)-15 is a pro-inflammatory cytokine that plays a crucial role in the pathogenesis ofPalabras claves:IL-15, Immunization, neutralizing antibodies, non-human primates, Rheumatoid ArthritisAutores:Alexey Llópiz-Arzuaga, Arrieta C.A., Besada-Pérez V., Castro-Velazco J., Eugenio Hardy, Geronimo H., Guillén-Nieto G.E., Martínez K., Martínez-Castillo R., Morera-Díaz Y., Moro A., Perea-Rodríguez S.E., Puente P., Ramos Y., Rodríguez-Álvarez Y., Santos-Savio A., Silva R., Vázquez M.Fuentes:scopusObtention and characterization of the recombinant simian Interleukin-15 in Escherichia coli for the preclinical assessment of an IL-15-based therapeutic vaccine
ArticleAbstract: Recombinant simian IL-15 (siIL-15) was obtained for the preclinical assessment of an anti-human IL-1Palabras claves:CTLL-2 and Kit 225 cells, E. coli, in vitro proliferation assays, Protein, recombinant siIL-15, VaccineAutores:Alexey Llópiz-Arzuaga, Besada-Pérez V., García-Lines D., Martínez-Cordovez K., Ramos-Gómez Y., Rodríguez-Álvarez Y., Santos-Savio A.Fuentes:googlescopus