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scopus(3)
Evaluation of transcriptional activity of caspase-3 gene as a marker of acute neurotoxicity in rat cerebellar granular cells
ArticleAbstract: Caspase-3 is a key protein involved in the classical apoptosis mechanism in neurons, as in many othePalabras claves:Acute toxicity, apoptosis, Caspase-3, Cell-cycle, Cerebellar granule neurons, Oxidative StressAutores:Alvira D., Antoni Camins, Folch J., Forsby A., López-Querol M., Pallás M., Rimbau V., Sureda F.X., Tajes M.Fuentes:scopusInhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons
ArticleAbstract: The biochemical pathways involved in neuronal cell death in Parkinson's disease are not completely cPalabras claves:apoptosis, Cerebellar granule cells, Cyclin dependent kinases, flavopiridol, Vitamin EAutores:Allgaier C., Alvira D., Antoni Camins, de Arriba S.G., Jiménez A., Matute C., Pallás M., Tajes M., Trullàs R., Verdaguer E.Fuentes:scopusInhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease
ArticleAbstract: In this study, the effects of melatonin on MPP+-treated cerebellar granule neurons (CGNs) in culturePalabras claves:apoptosis, Calpain, caspase, CDK5, Cerebellar granule cells, MPP +Autores:Acuña-Castroviejo D., Alvira D., Antoni Camins, Folch J., Pallás M., Tajes M., Verdaguer E.Fuentes:scopus