Mostrando 10 resultados de: 13
Filtros aplicados
Publisher
Journal of Pineal Research(3)
Neuroscience(2)
Experimental Gerontology(1)
Journal of Alzheimer's Disease(1)
Journal of Neural Transmission(1)
Área temáticas
Fisiología humana(12)
Enfermedades(7)
Bioquímica(3)
Sistemas fisiológicos específicos de los animales(3)
Farmacología y terapéutica(2)
Área de conocimiento
Neurología(8)
Neuropsicología(6)
Biología celular(4)
Bioquímica(3)
Biología molecular(2)
Objetivos de Desarrollo Sostenible
ODS 10: Reducción de las desigualdades(10)
ODS 12: Producción y consumo responsables(6)
ODS 17: Alianzas para lograr los objetivos(4)
ODS 9: Industria, innovación e infraestructura(4)
ODS 2: Hambre cero(1)
Origen
scopus(13)
Anti-aging properties of melatonin in an in vitro murine senescence model: Involvement of the sirtuin 1 pathway
ArticleAbstract: Sirtuin 1 is a member of the sirtuin family of protein deacetylases, which have attracted considerabPalabras claves:ADAM10, aging, Neurodegeneration, NFκB, Oxidative Stress, P53Autores:Antoni Camins, Gutiérrez-Cuesta J., Ortuo-Sahagún D., Pallás M., Tajes M.Fuentes:scopusActivation of Akt by lithium: Pro-survival pathways in aging
ArticleAbstract: The effects of lithium on senescence were investigated using the senescence-accelerated mouse pronePalabras claves:aging, Lithium chloride, Neurodegeneration, neuroprotection, SAMP8Autores:Antoni Camins, Casadesús G., Chou S.P., Pallás M., Smith M.A., Tajes M., Yeste-Velasco M., Zhu X.Fuentes:scopusEffects of melatonin in the brain of the senescence-accelerated mice-prone 8 (SAMP8) model
ArticleAbstract: Summary. Senescence-accelerated mice (SAM) represent an aging model establish by selective inbreedinPalabras claves:CDK5, GSK3beta, melatonin, TauAutores:Antoni Camins, Gutiérrez-Cuesta J., Jiménez A., Pallás M., Tajes M.Fuentes:scopusEvaluation of acute antiapoptotic effects of Li<sup>+</sup> in neuronal cell cultures
ArticleAbstract: Li+ exerts protective effect against several neurotoxins in neuronal cell preparations. Here we examPalabras claves:Autores:Alvira D., Antoni Camins, Folch J., Pallás M., Rimbau V., Tajes M., Verdaguer E., Yeste M.Fuentes:scopusEvaluation of potential pro-survival pathways regulated by melatonin in a murine senescence model
ArticleAbstract: We examined the effect of melatonin on pro-survival processes in three groups of mice. Untreated senPalabras claves:aging, Amyloid β, BRAIN, Cysteine proteases, Sirt1Autores:Antoni Camins, Coto-Montes A., Gutiérrez-Cuesta J., Jiménez A., Pallás M., Tajes M.Fuentes:scopusEvaluation of transcriptional activity of caspase-3 gene as a marker of acute neurotoxicity in rat cerebellar granular cells
ArticleAbstract: Caspase-3 is a key protein involved in the classical apoptosis mechanism in neurons, as in many othePalabras claves:Acute toxicity, apoptosis, Caspase-3, Cell-cycle, Cerebellar granule neurons, Oxidative StressAutores:Alvira D., Antoni Camins, Folch J., Forsby A., López-Querol M., Pallás M., Rimbau V., Sureda F.X., Tajes M.Fuentes:scopusInhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons
ArticleAbstract: The biochemical pathways involved in neuronal cell death in Parkinson's disease are not completely cPalabras claves:apoptosis, Cerebellar granule cells, Cyclin dependent kinases, flavopiridol, Vitamin EAutores:Allgaier C., Alvira D., Antoni Camins, de Arriba S.G., Jiménez A., Matute C., Pallás M., Tajes M., Trullàs R., Verdaguer E.Fuentes:scopusInhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease
ArticleAbstract: In this study, the effects of melatonin on MPP+-treated cerebellar granule neurons (CGNs) in culturePalabras claves:apoptosis, Calpain, caspase, CDK5, Cerebellar granule cells, MPP +Autores:Acuña-Castroviejo D., Alvira D., Antoni Camins, Folch J., Pallás M., Tajes M., Verdaguer E.Fuentes:scopusNeuronal cell cycle re-entry markers are altered in the senescence accelerated mouse P8 (SAMP8)
ArticleAbstract: Senescence-accelerated mice 8 (SAMP8), a model of aging, display many established pathological featuPalabras claves:aging, Alzheimer's disease, CDK5, cell cycle, GSK3β, TauAutores:Antoni Camins, Casadesús G., Gutiérrez-Cuesta J., Jiménez A., Lee H.g., Ortuo-Sahagún D., Pallás M., Smith M.A., Tajes M.Fuentes:scopusNeuroprotective role of intermittent fasting in senescence-accelerated mice P8 (SAMP8)
ArticleAbstract: Dietary interventions have been proposed as a way to increase lifespan and improve health. The senesPalabras claves:ADAM10, ageing, BDNF, Neurodegeneration, NFκB, Sirtuin 1Autores:Antoni Camins, Folch J., Gutiérrez-Cuesta J., Jiménez A., Junyent F., Lau A., Ortuo-Sahagún D., Pallás M., Tajes M., Verdaguer E.Fuentes:scopus