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Marine Drugs(2)
Biotechnology and Applied Biochemistry(1)
Crystals(1)
Journal of Molecular Modeling(1)
Journal of Structural Biology(1)
Canonical or noncanonical? Structural plasticity of serine protease-binding loops in Kunitz-STI protease inhibitors
ArticleAbstract: The Kunitz-Soybean Trypsin Inhibitor (Kunitz-STI) family is a large family of proteins with most ofPalabras claves:canonical inhibitors, Kunitz, noncanonical inhibitors, protease inhibitors, serine proteaseAutores:Berry C., Eduardo Tejera, Pons T., Vinicio Danilo Armijos-Jaramillo, Yasel GuerraFuentes:googlescopusGeneration of an affinity matrix useful in the purification of natural inhibitors of plasmepsin II, an antimalarial-drug target
ArticleAbstract: An affinity matrix containing the antimalarial drug target Plm II (plasmepsin II) as ligand was genePalabras claves:Antimalarial-drug target, Plasmepsin II inhibitor, Plasmodium (malarial parasite), Plexaura homomalla (black sea rod), Xestospongia muta (giant barrel sponge)Autores:Berry C., Chávez M.d.l.A., García B., Hernández-Zanui A., Mendiola J., Otero A.J., Ramírez A.R., Yasel GuerraFuentes:googlescopusEnzyme Inhibitors from Gorgonians and Soft Corals
ReviewAbstract: For decades, gorgonians and soft corals have been considered promising sources of bioactive compoundPalabras claves:enzyme inhibitors, enzyme kinetics, Gorgonian, inhibitor characterization, Natural products, soft coral, STRENDA guidelinesAutores:Andrea Córdova-Isaza, Salas-Sarduy E., Sofía Jiménez-Mármol, Yasel GuerraFuentes:googlescopusNovel devices for transporting protein crystals to the synchrotron facilities and thermal protection of protein crystals
ArticleAbstract: In this article, we use novel and non-conventional devices, based on polyolefins that help to increaPalabras claves:Apo-transferrin, Conventional and non-conventional methods of protein crystallization, Crystal growth in solution, Ferritin, Gel-growth, Glucose isomerase, Insulin, Lysozyme, xylanaseAutores:Campos-Escamilla C., Cuéllar-Cruz M., Demitri N., Flores-Ibarra A., Moreno A., Polentarutti M., Rudino-Pinera E., Yasel GuerraFuentes:googlescopusIdentification of tight-binding plasmepsin II and falcipain 2 inhibitors in aqueous extracts of marine invertebrates by the combination of enzymatic and interaction-based assays
ArticleAbstract: Natural products from marine origin constitute a very promising and underexplored source of interestPalabras claves:Combined screening strategy, Falcipain 2, Plasmepsin II, Plasmodium falciparum, Tight-binding protease inhibitorAutores:Avilés F.X., Cortés G.C., Planes M.A.C., Salas-Sarduy E., Yasel GuerraFuentes:googlescopusPbkp_redicting functional residues of the Solanum lycopersicum aspartic protease inhibitor (SLAPI) by combining sequence and structural analysis with molecular docking
ArticleAbstract: The Solanum lycopersicum aspartic protease inhibitor (SLAPI), which belongs to the STI-Kunitz familyPalabras claves:Aspartic protease inhibitor, Comparative 3D modeling, Functional residue identification, Protein-protein docking, Protein-protein interface, STI-Kunitz inhibitorAutores:Berry C., Pons T., Valiente P.A., Yasel GuerraFuentes:googlescopusStructures of a bi-functional Kunitz-type STI family inhibitor of serine and aspartic proteases: Could the aspartic protease inhibition have evolved from a canonical serine protease-binding loop?
ArticleAbstract: Bi-functional inhibitors from the Kunitz-type soybean trypsin inhibitor (STI) family are glycosylatePalabras claves:Aspartic protease inhibitors, Bi-functional inhibitors, Kunitz-type STI family inhibitors, Plant protease inhibitors, β-Trefoil foldAutores:Berry C., Pons T., Rudino-Pinera E., Valiente P.A., Yasel GuerraFuentes:googlescopus