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Molecular Oncology Principles and Recent Advances(4)
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Circulating miRNome detection analysis reveals 537 miRNAS in plasma, 625 in extracellular vesicles and a discriminant plasma signature of 19 miRNAs in children with retinoblastoma from which 14 are also detected in corresponding primary tumors
ArticleAbstract: miRNAs regulate post-transcriptional gene expression in metazoans, and thus are involved in many funPalabras claves:Autores:Alvarez-Suarez D.E., Cabrera-Muñoz L., Castro-Magdonel B.E., Durán-Figueroa N., García-Vega D., Hernández-Angeles A., Javier Camacho, Lara-Molina C., Medina-Sanson A., Orjuela M., Orozco-Romero M.D.J., Ponce-castañeda M.V., Sadowinski-Pine S., Vázquez Y.Fuentes:scopusAstemizole Synergizes Calcitriol Antiproliferative Activity by Inhibiting CYP24A1 and Upregulating VDR: A Novel Approach for Breast Cancer Therapy
ArticleAbstract: Background: Calcitriol antiproliferative effects include inhibition of the oncogenic ether-à-go-go-1Palabras claves:Autores:Avila-Chávez E., David B., Díaz L., Gamboa-Dominguez A., García-Becerra R., García-Quiroz J., Halhali A., Javier Camacho, Larrea F., Medina-Franco H., Ordaz-Rosado D., Rivas-Suárez M., Rodríguez P., Santos-Martínez N.Fuentes:scopusAstemizole inhibits cell proliferation in human prostate tumorigenic cells expressing ether à-go-go-1 potassium channels
ArticleAbstract: Prostate cancer (PC) is the main cause of cancer mortality in men worldwide. Therefore, novel treatmPalabras claves:Anti-histamine, Astemizole, Eag1, ion channels, Prostate cancerAutores:Bernal-Ramos G., Chávez-lópez M.d.G., Garrido E., Hernández-gallegos E., Javier Camacho, Sánchez-Pérez Y., Vera E., Zúñiga-García V.Fuentes:scopusAstemizole-based anticancer therapy for hepatocellular carcinoma (HCC), and Eag1 channels as potential early-stage markers of HCC
ArticleAbstract: Hepatocellular carcinoma (HCC) has very poor prognosis. Astemizole has gained great interest as a poPalabras claves:Astemizole, Eag1, Liver cancer, Liver cirrhosis, Potassium channels, tumor markersAutores:Acuña-Macías I., Caro-Sánchez C.H., Chiliquinga A.J., de Guadalupe Chávez-López M., Díaz-Chávez J., Gariglio P., Hernández-gallegos E., Herrera L.A., Javier Camacho, Pérez-Carreón J.I., Zúñiga-García V.Fuentes:scopusAstemizole: An old anti-histamine as a new promising anti-cancer drug
ReviewAbstract: Mortality-to-incidence ratio in cancer patients is extremely high, positioning cancer as a major cauPalabras claves:Anticancer drugs, Astemizole, Eag1, Erg, Histamine, Potassium channels, QT-intervalAutores:García-Quiroz J., Javier CamachoFuentes:scopusAntiproliferative and proapoptotic effects of astemizole on cervical cancer cells
ArticleAbstract: Objective: Cervical cancer is a major cause of mortality among women in developing countries. Thus,Palabras claves:Astemizole, Cervical Cancer, Ether à-go-go, Imipramine, Potassium channelsAutores:de Guadalupe Chávez-López M., Gariglio P., Hernández-gallegos E., Javier Camacho, Vázquez-Sánchez A.Y.Fuentes:scopusCalcitriol down-regulates human ether à go-go 1 potassium channel expression in cervical cancer cells
ArticleAbstract: Background/Aim: Human ether à-go-go-1 (EAG1) potassium channels are promising anticancer targets. CaPalabras claves:Calcitriol, Cervical Cancer, Eag1, PLACENTA, Potassium channels, Prostate cancer, vitamin DAutores:Avila-Chávez E., David B., Díaz L., Fernando L., García-Becerra R., Halhali A., Javier Camacho, Ordaz-Rosado D., Rodríguez-Rasgado J.A., Steinmeyer A., Zügel U.Fuentes:scopusCalcitriol inhibits Ether-à go-go potassium channel expression and cell proliferation in human breast cancer cells
ArticleAbstract: Antiproliferative actions of calcitriol have been shown to occur in many cell types; however, littlePalabras claves:Astemizole, Breast Cancer, K channels +, TEI-9647, VDR, vitamin DAutores:Arrecillas M., Avila-Chávez E., Bargallo E., David B., Díaz L., García-Becerra R., Halhali A., Javier Camacho, Larrea F., Morales A., Ordaz-Rosado D., Ortiz C.S.Fuentes:scopusCalcitriol restores antiestrogen responsiveness in estrogen receptor negative breast cancer cells: A potential new therapeutic approach
ArticleAbstract: Background: Approximately 30% of breast tumors do not express the estrogen receptor (ER) α, which isPalabras claves:Breast Cancer, Calcitriol, Estrogen receptor, Hormonal therapy, VDRAutores:Avila-Chávez E., David B., Díaz L., Esparza-López J., García-Becerra R., García-Quiroz J., Halhali A., Ibarra-Sánchez M., Javier Camacho, Larrea F., Medina-Franco H., Ordaz-Rosado D., Santos-Martínez N.Fuentes:scopusCalcium-activated potassium channels as potential early markers of human cervical cancer
ArticleAbstract: Cervical cancer is a major cause of cancer-associated mortality in women in developing countries. ThPalabras claves:Calcium-activated potassium channels, Cervical Cancer, estrogens, Ether à-go-go-1 channels, human papilloma virusAutores:Gamboa-Dominguez A., Gariglio P., Javier Camacho, Lambert P., Ramírez A., Vera E.Fuentes:scopus