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Astemizole-based anticancer therapy for hepatocellular carcinoma (HCC), and Eag1 channels as potential early-stage markers of HCC
ArticleAbstract: Hepatocellular carcinoma (HCC) has very poor prognosis. Astemizole has gained great interest as a poPalabras claves:Astemizole, Eag1, Liver cancer, Liver cirrhosis, Potassium channels, tumor markersAutores:Acuña-Macías I., Caro-Sánchez C.H., Chiliquinga A.J., de Guadalupe Chávez-López M., Díaz-Chávez J., Gariglio P., Hernández-gallegos E., Herrera L.A., Javier Camacho, Pérez-Carreón J.I., Zúñiga-García V.Fuentes:scopusAstemizole: An old anti-histamine as a new promising anti-cancer drug
ReviewAbstract: Mortality-to-incidence ratio in cancer patients is extremely high, positioning cancer as a major cauPalabras claves:Anticancer drugs, Astemizole, Eag1, Erg, Histamine, Potassium channels, QT-intervalAutores:García-Quiroz J., Javier CamachoFuentes:scopusAntiproliferative and proapoptotic effects of astemizole on cervical cancer cells
ArticleAbstract: Objective: Cervical cancer is a major cause of mortality among women in developing countries. Thus,Palabras claves:Astemizole, Cervical Cancer, Ether à-go-go, Imipramine, Potassium channelsAutores:de Guadalupe Chávez-López M., Gariglio P., Hernández-gallegos E., Javier Camacho, Vázquez-Sánchez A.Y.Fuentes:scopusCalcitriol down-regulates human ether à go-go 1 potassium channel expression in cervical cancer cells
ArticleAbstract: Background/Aim: Human ether à-go-go-1 (EAG1) potassium channels are promising anticancer targets. CaPalabras claves:Calcitriol, Cervical Cancer, Eag1, PLACENTA, Potassium channels, Prostate cancer, vitamin DAutores:Avila-Chávez E., David B., Díaz L., Fernando L., García-Becerra R., Halhali A., Javier Camacho, Ordaz-Rosado D., Rodríguez-Rasgado J.A., Steinmeyer A., Zügel U.Fuentes:scopusCell cycle-related changes in the conducting properties of r-eag K<sup>+</sup> channels
ArticleAbstract: Release from arrest in G2 phase of the cell cycle causes profound changes in rat ether-a-go-go (r-eaPalabras claves:cell cycle, CHO cells, electrophysiology, Potassium channels, XENOPUS LAEVISAutores:Brüggemann A., Javier Camacho, Pardo L.A., Stühmer W.Fuentes:scopusEag1 channels as potential cancer biomarkers
ReviewAbstract: Cancer is a leading cause of death worldwide. New early tumor markers are needed to treat the diseasPalabras claves:Cervical Cancer, Colon cancer, estrogens, Ether à-go-go, human papilloma virus, Leukemia, Potassium channels, Prognostic markers, tumor markersAutores:Acuña-Macías I., Javier Camacho, Rodríguez-Rasgado J.A.Fuentes:scopusEag1 gene and protein expression in human retinoblastoma tumors and its regulation by pRb in HeLa cells
ArticleAbstract: Retinoblastoma is the most common pediatric intraocular malignant tumor. Unfortunately, low cure ratPalabras claves:Astemizole, Eag1 channels, KCNH1, Kv10.1, Potassium channels, Retinoblastoma, tumor suppressorAutores:Avalos-fuentes A., Cabrera-muñoz M.d.L., Castro-Magdonel B.E., Chávez-lópez M.d.G., Escobar Y., Garrido E., Hernández-gallegos E., Javier Camacho, Ortiz C.S., Ponce-castañeda M.V., Sanchez-Ramos J., Vera E., Zúñiga-García V.Fuentes:scopusEag1 potassium channels as markers of cervical dysplasia
ArticleAbstract: Human ether à-go-go 1 (Eag1) potassium channels are potential tumor markers and therapeutic targetsPalabras claves:Cervical Cancer, estrogens, Human ether à-go-go 1, Potassium channels, tumor markersAutores:Aguilar-Guadarrama R., Gamboa-Dominguez A., Garcia-Villa E., Gariglio P., Hernández-gallegos E., Hinojosa L.M., Javier Camacho, Martínez-Benítez B., Montante-Montes D., Ortiz C.S., Pardo L.A., Ramírez A., Saqui-Salces M., Solís-Pancoatl M., Stühmer W.Fuentes:scopusEffect of extracellular matrix on adhesion, viability, actin cytoskeleton and K<sup>+</sup> currents of cells expressing human ether à go-go channels
ArticleAbstract: Ether à go-go (EAG) potassium channels possess oncogenic properties and have gained great interest aPalabras claves:actin, Cáncer, collagen, Cytoskeleton, Ether à-go-go, extracellular matrix, fibronectin, Potassium channels, ProliferationAutores:Azorín E., Delgadillo D.M., Gomora J.C., Hernández-gallegos E., Javier Camacho, Mendoza-Garrido M.E., Solano-Agama C., Toral C.Fuentes:scopusDifferential regulation of human eagl channel expression by serum and epidermal growth factor in lung and breast cancer cells
ArticleAbstract: Oncogenic ether à-go-go-1 (Eag1) potassium channels are overexpressed in most primary human solid tuPalabras claves:EGF, Epidermal growth factor, ERK 1/2, Ether à-go-go, lung cancer, Potassium channels, Serum deprivationAutores:Acuña-Macías I., Javier Camacho, Mendoza-Garrido M.E., Vázquez-Sánchez A.Y., Vera E.Fuentes:scopus