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Circulating miRNome detection analysis reveals 537 miRNAS in plasma, 625 in extracellular vesicles and a discriminant plasma signature of 19 miRNAs in children with retinoblastoma from which 14 are also detected in corresponding primary tumors
ArticleAbstract: miRNAs regulate post-transcriptional gene expression in metazoans, and thus are involved in many funPalabras claves:Autores:Alvarez-Suarez D.E., Cabrera-Muñoz L., Castro-Magdonel B.E., Durán-Figueroa N., García-Vega D., Hernández-Angeles A., Javier Camacho, Lara-Molina C., Medina-Sanson A., Orjuela M., Orozco-Romero M.D.J., Ponce-castañeda M.V., Sadowinski-Pine S., Vázquez Y.Fuentes:scopusCirrhosis induced by thioacetamide is prevented by stevia. Molecular mechanisms
ArticleAbstract: This study aimed to investigate the ability of stevia leaves to prevent thioacetamide (TAA)-inducedPalabras claves:Anti-Inflammatory, FIBROSIS, Liver, Stevioside, sweetenerAutores:Casas-Grajales S., Diaz-Ruiz A., Flores-Beltrán R.E., Galindo-Gómez S., Hernández-Aquino E., Javier Camacho, Montes S., Muriel P., Ramos-Tovar E., Tsutsumi V., Vera-Aguilar E.Fuentes:scopusAstemizole Synergizes Calcitriol Antiproliferative Activity by Inhibiting CYP24A1 and Upregulating VDR: A Novel Approach for Breast Cancer Therapy
ArticleAbstract: Background: Calcitriol antiproliferative effects include inhibition of the oncogenic ether-à-go-go-1Palabras claves:Autores:Avila-Chávez E., David B., Díaz L., Gamboa-Dominguez A., García-Becerra R., García-Quiroz J., Halhali A., Javier Camacho, Larrea F., Medina-Franco H., Ordaz-Rosado D., Rivas-Suárez M., Rodríguez P., Santos-Martínez N.Fuentes:scopusAstemizole inhibits cell proliferation in human prostate tumorigenic cells expressing ether à-go-go-1 potassium channels
ArticleAbstract: Prostate cancer (PC) is the main cause of cancer mortality in men worldwide. Therefore, novel treatmPalabras claves:Anti-histamine, Astemizole, Eag1, ion channels, Prostate cancerAutores:Bernal-Ramos G., Chávez-lópez M.d.G., Garrido E., Hernández-gallegos E., Javier Camacho, Sánchez-Pérez Y., Vera E., Zúñiga-García V.Fuentes:scopusAstemizole-based anticancer therapy for hepatocellular carcinoma (HCC), and Eag1 channels as potential early-stage markers of HCC
ArticleAbstract: Hepatocellular carcinoma (HCC) has very poor prognosis. Astemizole has gained great interest as a poPalabras claves:Astemizole, Eag1, Liver cancer, Liver cirrhosis, Potassium channels, tumor markersAutores:Acuña-Macías I., Caro-Sánchez C.H., Chiliquinga A.J., de Guadalupe Chávez-López M., Díaz-Chávez J., Gariglio P., Hernández-gallegos E., Herrera L.A., Javier Camacho, Pérez-Carreón J.I., Zúñiga-García V.Fuentes:scopusAstemizole: An old anti-histamine as a new promising anti-cancer drug
ReviewAbstract: Mortality-to-incidence ratio in cancer patients is extremely high, positioning cancer as a major cauPalabras claves:Anticancer drugs, Astemizole, Eag1, Erg, Histamine, Potassium channels, QT-intervalAutores:García-Quiroz J., Javier CamachoFuentes:scopusAn aqueous extract of Stevia rebaudiana variety Morita II prevents liver damage in a rat model of cirrhosis that mimics the human disease
ArticleAbstract: Introduction and aim: Stevia has exhibited antioxidant, antihyperglycemic, antihypertensive and antiPalabras claves:Anti-Inflammatory, Antifibrotic, antioxidant, FIBROSIS, hepatic stellate cellAutores:Flores-Beltrán R.E., Galindo-Gómez S., Javier Camacho, Muriel P., Ramos-Tovar E., Tsutsumi V.Fuentes:scopusAntioxidant and immunomodulatory activity induced by stevioside in liver damage: In vivo, in vitro and in silico assays
ArticleAbstract: Aims: Stevioside is a diterpenoid obtained from the leaves of Stevia rebaudiana (Bertoni) that exhibPalabras claves:Cocultures, docking, Immunomodulatory, Nrf2, Stevioside, TAAAutores:Alvarez-Suarez D.E., Casas-Grajales S., Cerda-García-Rojas C.M., Chávez-Estrada E., Hernández-Aquino E., Javier Camacho, Lakshman M.R., Muriel P., Ramos-Tovar E., Reyes-Gordillo K., Tsutsumi V.Fuentes:scopusAntiproliferative and proapoptotic effects of astemizole on cervical cancer cells
ArticleAbstract: Objective: Cervical cancer is a major cause of mortality among women in developing countries. Thus,Palabras claves:Astemizole, Cervical Cancer, Ether à-go-go, Imipramine, Potassium channelsAutores:de Guadalupe Chávez-López M., Gariglio P., Hernández-gallegos E., Javier Camacho, Vázquez-Sánchez A.Y.Fuentes:scopusA dual and opposite effect of Calendula officinalis flower extract: Chemoprotector and promoter in a rat hepatocarcinogenesis model
ArticleAbstract: Calendula officinalis extracts have protective and cytotoxic effects. We previously reported the duaPalabras claves:Antigenotoxicity, CALÉNDULA OFFICINALIS, Chemopreventive effect, genotoxicity, Hepatocarcinogenesis, Hormesis, PromoterAutores:Alemán-Lazarini L., Arce-Popoca E., Barajas-Farias L.M., Cruz-Jiménez F.C., Fattel-Fazenda S., Hernández-García S., Javier Camacho, Pérez-Carreón J.I., Salcido-Neyoy M., Villa-Treviño S.Fuentes:scopus