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CIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo
ArticleAbstract: Protein Kinase CK2 is a serine-threonine kinase frequently deregulated in many human tumors. Here, wPalabras claves:apoptosis, Cancer targeted therapy, Casein kinase 2Autores:Acevedo B.E., Alonso D.F., Ariosa J., Bacardí D.M., Baladron I., Besada-Pérez V., Betancourt L., Castellanos L.R., Cosme K., Cruz M., Díaz A., Falcón-Cama V., Farina H., Garay H.E., Gil J., Gómez D., Gómez R., González L.J., Hernández I., Herrera L., López C., López-Mola E., López-Saura P.A., Marcelo J.L., Mendoza O., Perea-Rodríguez S.E., Perera Y., Puchades Y., Reyes O., Rodriguez A., Sánchez A., Santana A., Serrano J.M., Sigman H., Silva R., Solares M., Thelvia I. Ramos Gómez, Valenzuela-Silva C.M.Fuentes:googlescopusActive immunotherapy in lung cancer, new therapeutic options
OtherAbstract:Palabras claves:Autores:Thelvia I. Ramos GómezFuentes:scopusAdjuvant interferon gamma in patients with pulmonary atypical Mycobacteriosis: A randomized, double-blind, placebo-controlled study
ArticleAbstract: Background: High antibiotic resistance is described in atypical Mycobacteriosis, mainly by MycobactePalabras claves:Autores:Bello-Rivero I., Fernández-Olivera N., García-García I., González-Méndez L., Jiménez-Madrigal G., López-Saura P.A., Martínez-Sánchez G., Milanés-Virelles M.T., Rodríguez-Acosta C., Sánchez-de la Osa R.B., Santos-Herrera Y., Thelvia I. Ramos Gómez, Valdés-Quintana M., Valenzuela-Silva C.M.Fuentes:googlescopusLOX-1 in cardiovascular diseases, future therapeutic perspectives
ArticleAbstract: The low-density oxidized lipoprotein lectin-1 (LOX-1) receptor, also known as OLR-1, is a scavengerPalabras claves:atherosclerosis, dyslipidemia, endothelial dysfunction, LOX-1 lectin-like OxLDL receptor 1, Oxidized low-density lipoprotein, Soluble LOX-1Autores:Alonso J.R.T., Thelvia I. Ramos GómezFuentes:scopusSafety and preliminary efficacy data of a novel Casein Kinase 2 (CK2) peptide inhibitor administered intralesionally at four dose levels in patients with cervical malignancies
ArticleAbstract: Background: Cervical cancer is now considered the second leading cause of death among women worldwidPalabras claves:Autores:Acevedo B.E., Alonso D.F., Baladron I., Castillo D., Díaz A., Gómez R., González C.A., Herrera L., López-Saura P.A., Perea-Rodríguez S.E., Santana A., Sigman H., Solares A.M., Thelvia I. Ramos Gómez, Valenzuela-Silva C.M.Fuentes:googlescopusRecombinant gamma interferon for the treatment of pulmonary and mycobacterial diseases
ArticleAbstract: An increased antibiotic resistance is described for Mycobacterium tuberculosis and atypical mycobactPalabras claves:BCG, Idiopathic pulmonary fibrosis, Interferon gamma, Lymphadenitis, Multidrug-resistant pulmonary tuberculosis, Mycobacteria, Mycobacterium avium complexAutores:Abreu G., Cayón I., García I., González-Méndez L., Jiménez G., López P., Milanés M.T., Sánchez R.B., Santos Y., Thelvia I. Ramos Gómez, Valdés M., Valenzuela-Silva C.M.Fuentes:googlescopusRepeated administration of hepatitis C virus core-encoding plasmid to mice does not necessarily increase the immune response generated against this antigen
ArticleAbstract: DNA immunization is a promising approach in generating immune responses to infectious pathogens in mPalabras claves:Genetic immunization, HCV, Lymphocyte proliferation, nucleocapsid, VaccineAutores:Alvarez J.C., Alvarez-Lajonchere L., Dueñas-Carrera S., Morales J., Pichardo D., Thelvia I. Ramos GómezFuentes:scopusReport of two cases of suppurated lymphadenitis caused by Bacillus Calmette-Guerin treated with recombinant γ-interferon
ArticleAbstract: Suppurative lymphadenitis is a non frequent complication following Bacillus Calmette-Guerin (BCG) vaPalabras claves:BCG, Interferon gamma, LymphadenitisAutores:Fernández G.F., García-García I., Grau I.M., López-Saura P.A., Méndez L.G., Suárez G.A., Thelvia I. Ramos GómezFuentes:scopusPresence of the G1138A mutation in the FGFR3 coding gene in a group of Cuban achondroplasia patients
ArticleAbstract: Achondroplasia, inherited as an autosomal dominant trait, is the most common human skeletal dysplasiPalabras claves:Achondroplasia, Autosomal dominant, FGFR3, Hipoachondroplasia, Osteochondrodysplasias, Thanatophoric dysplasiaAutores:Avella A.B., Baute L.H., Fernandez S.O., Mesa T.C., Peralta E.M., Thelvia I. Ramos GómezFuentes:googlescopus