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Innovative three-step microwave-promoted synthesis of N-propargyltetrahydroquinoline and 1,2,3-triazole derivatives as a potential factor Xa (FXA) inhibitors: Drug design, synthesis, and biological evaluation.
ArticleAbstract: The coagulation cascade is the process of the conversion of soluble fibrinogen to insoluble fibrin tPalabras claves:1,2,3-triazole, Cell viability assay, Coagulation parameters, Factor Xa inhibitors, Microwave-assisted synthesis, N-propargyltetrahydroquinolineAutores:Castillo F., Charbe N., Duarte Y., Fabián Santana-Romo, Lagos C.F., Maestro M.A., Moglie Y., Zacconi F.C.Fuentes:scopusSurfing the blood coagulation cascade: Insight into the vital factor xa
ReviewAbstract: Factor Xa (FXa) plays a key role in haemostasis, it is a central part of the blood coagulation cascaPalabras claves:anticoagulants, Coagulation cascade, Direct FXa inhibitors, FXa, FXa reversal agents, Synthetic inhibitorsAutores:Fabián Santana-Romo, Núñez-Navarro N.E., Parra L.P., Zacconi F.C.Fuentes:scopusAssessment of hepatic fatty acids during non-alcoholic steatohepatitis progression using magnetic resonance spectroscopy
ArticleAbstract: Introduction and objectives: Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of livPalabras claves:Choline-deficient, l-amino acid-defined (CDAA), Gas chromatography with mass spectrometry (GC–MS), Magnetic resonance spectroscopy, Mouse model, Non-alcoholic fatty liver disease (NAFLD), SteatohepatitisAutores:Andia M.E., Arrese M., Botnar R., Cabrera D., Eykyn T.R., Fabián Mauricio Santana Romo, Fabián Santana-Romo, Lavin B., Oyarzún J.E., Phinikaridou A., Uribe S.A., Xavier A., Zacconi F.C.Fuentes:googlescopus