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Cytotoxic and apoptosis-inducing effect of ent-15-oxo-kaur-16-en-19-oic acid, a derivative of grandiflorolic acid from Espeletia schultzii
ArticleAbstract: ent-Kaurenic acid and many natural derivatives of this diterpene are known to have interesting bioloPalabras claves:apoptosis, ent-5-Oxo-kaur-16-en-19-oic acid, ent-Kaurenoids, Espeletia schultzii, Espeletiinae, Frailejón, PC-3 cell lineAutores:Arvelo F.A., Galindo-Castro I., Monsalve M., Nardy Diez, Rodrigues J.R., Ruiz Y., Usubillaga A.Fuentes:googlescopusEnvenomation by the scorpion Tityus breweri in the Guayana Shield, Venezuela: Report of a case, efficacy and reactivity of antivenom, and proposal for a toxinological partitioning of the Venezuelan scorpion fauna
ArticleAbstract: Objectives.- Scorpion envenomation is a common public health problem in Venezuela. We report an envePalabras claves:Guayana, scorpion toxin, scorpion venom, Scorpionism, Tityus, Tityus breweri, VENEZUELAAutores:Adolfo Borges, De Sousa L., Faks J.G., Nardy Diez, Op den Camp H.J.M., Rojas-Runjaic F.J.M.Fuentes:googlescopusSnake venomics and antivenomics of Bothrops colombiensis, a medically important pitviper of the Bothrops atrox-asper complex endemic to Venezuela: Contributing to its taxonomy and snakebite management
ArticleAbstract: The taxonomic status of the medically important pitviper of the Bothrops atrox-asper complex endemicPalabras claves:Antibothropic and anticrotalic ABC antivenom, Antivenomics, Bothrops colombiensis, Mass spectrometry, N-terminal sequencing, Polyvalent (crotalinae) ICP antivenom, proteomics, Snake venom protein families, Snake venomics, Viperid toxinsAutores:Adolfo Borges, Alape-Girón A., Calvete J.J., De Sousa L., Escolano J., Faks J.G., Flores-Díaz M., Gutiérrez J.M., Kiriakos D., Nardy Diez, Sánchez E., Sanz L., Segura A.Fuentes:googlescopus