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G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo
ArticleAbstract: Intronic GGGGCC repeat expansions in C9orf72 are the most common known cause of frontotemporal demenPalabras claves:amyotrophic lateral sclerosis, C9orf72, frontotemporal dementia, G-quadruplexAutores:Abdelkarim S., Balendra R., Boykin D.W., Calvo A., Chio A., Clarke M., Clayton E.L., Farahat A.A., Fratta P., Heslegrave A., Houlden H., Isaacs A.M., Ismail M.A., Javier Gilbert Jaramillo, Konrad M.T., Mitchell J.S., Moens T.G., Neidle S., Niccoli T., Nicoll A.J., Parkinson G., Partridge L., Patani R., Polke J.M., Preza E., Simone R., Stephens C.E., Vo T., Wilson K.M., Wilson W.D., Woodling N.S., Wray S., Zetterberg H.Fuentes:scopusSurvival in juvenile shrimps (Penaeus vannamei) exposed to inactive against active white spot virus: A challenge bioassay perspective
ArticleAbstract: White spot syndrome virus (WSSV) has damaged the Ecuadorian shrimp culture industry severely. The shPalabras claves:Aquaculture, infection, Penaeus Vannamei, survival rate, WHITE SPOT VIRUSAutores:Fabrizio Marcillo-Morla, Javier Gilbert Jaramillo, Marcelo Muñoz, Marcillo Gallino Ecuador, Muñoz-Naranjo D.Fuentes:scopus