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Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling
ArticleAbstract: The Ebola virus (EBOV) VP35 protein blocks the virus-induced phosphorylation and activation of interPalabras claves:Autores:Basler C.F., Gale M., Hartman A., Kimberlin C., Loo Y.M., Martínez-Sobrido L., Saphire E., Washington B. CárdenasFuentes:googlescopusEbola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKε and TBK-1
ArticleAbstract: The Ebola virus (EBOV) VP35 protein antagonizes the early antiviral alpha/beta interferon (IFN-α/β)Palabras claves:Autores:Basler C.F., Prins K.C., Washington B. CárdenasFuentes:googlescopusMutations abrogating VP35 interaction with double-stranded RNA render Ebola virus avirulent in guinea pigs
ArticleAbstract: Ebola virus (EBOV) protein VP35 is a double-stranded RNA (dsRNA) binding inhibitor of host interferoPalabras claves:Autores:Amarasinghe G.K., Basler C.F., Delpeut S., Leung D.W., Prins K.C., Ramanan P., Reid S.P., Reynard O., Volchkov V.E., Volchkova V.A., Washington B. CárdenasFuentes:googlescopusNuclear localization of the Nipah virus W protein allows for inhibition of both virus- and Toll-like receptor 3-triggered signaling pathways
ArticleAbstract: The Nipah virus V and W proteins, which are encoded by the P gene via RNA editing, have a common N-tPalabras claves:Autores:Basler C.F., Palese P., Shaw M., Washington B. Cárdenas, Zamarin D.Fuentes:googlescopusInhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus
ArticleAbstract: The retinoic acid-inducible gene I product (RIG-I) has been identified as a cellular sensor of RNA vPalabras claves:Autores:Gale M., García-Sastre A., Loo Y.M., Martínez-Sobrido L., Mibayashi M., Washington B. CárdenasFuentes:googlescopus