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Frontiers in Plant Science(3)
Biological and Pharmaceutical Bulletin(1)
Biotechnology and Bioengineering(1)
Fifty Years of Cytochrome P450 Research(1)
Journal of Natural Medicines(1)
Comparative Analysis of NADPH-Cytochrome P450 Reductases From Legumes for Heterologous Production of Triterpenoids in Transgenic Saccharomyces cerevisiae
ArticleAbstract: Triterpenoids are plant specialized metabolites with various pharmacological activities. They are wiPalabras claves:cytochrome P450 monooxygenases (CYP), heterologous production, Legumes, NADPH-cytochrome P450 reductases (CPR), Saccharomyces Cerevisiae, TriterpenoidsAutores:Chikugo A., Ery Odette Fukushima, Istiandari P., Muranaka T., Seki H., Srisawat P., Suzuki H., Tamura K., Yasumoto S.Fuentes:googlescopusComparative analysis of CYP716A subfamily enzymes for the heterologous production of C-28 oxidized triterpenoids in transgenic yeast
ArticleAbstract: Several enzymes of the CYP716A subfamily have been reported to be involved in triterpenoid biosynthePalabras claves:Beta Vulgaris, Coffea Arábica, CYP716A, Olea europaea, TriterpenoidAutores:Ery Odette Fukushima, Muranaka T., Ohyama K., Seki H., Suzuki H., Umemoto N.Fuentes:googlescopusArtemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasites
ReviewAbstract: Malaria is a worldwide disease caused by Plasmodium parasites. A sesquiterpene endoperoxide artemisiPalabras claves:Artemisia annua, Artemisinin, MALARIA, Metabolic engineering, Mode of action, Resistant parasitesAutores:Ery Odette Fukushima, Muangphrom P., Muranaka T., Seki H.Fuentes:googlescopusFunctional characterization of CYP716 family P450 enzymes in triterpenoid biosynthesis in tomato
ArticleAbstract: Triterpenoids are a group of structurally diverse specialized metabolites that frequently show usefuPalabras claves:C-28 oxidase, C-6β oxidase, CYP716 family, cytochrome P450 monooxygenase, Tomato, Triterpenoid biosynthesisAutores:Ery Odette Fukushima, Muranaka T., Seki H., Shimizu Y., Yasumoto S.Fuentes:googlescopusIdentification and genome organization of saponin pathway genes from a wild crucifer, and their use for transient production of saponins in Nicotiana benthamiana
ArticleAbstract: The ability to evolve novel metabolites has been instrumental for the defence of plants against antaPalabras claves:Barbarea vulgaris, EVOLUTION, Metabolic engineering, Nicotiana benthamiana, oxidosqualene cyclases, P450, Synthetic biology, UDP-glycosyltransferasesAutores:Andersen S.B., Augustin J.M., Bak S., Erthmann P., Ery Odette Fukushima, Hauser T.P., Khakimov B., Kuzina V., Muranaka T., Olsen C.E., Scholtalbers J., Volpin H.Fuentes:googlescopusIdentification of oxidosqualene cyclases from the medicinal legume tree Bauhinia forficata: a step toward discovering preponderant α-amyrin-producing activity
ArticleAbstract: Triterpenoids are widely distributed among plants of the legume family. However, most studies have fPalabras claves:Bauhinia forficata, non-model legume, oxidosqualene cyclase, Triterpenoid, α-amyrinAutores:Ery Odette Fukushima, Muranaka T., Robertlee J., Seki H., Srisawat P., Suzuki H., Yasumoto S.Fuentes:googlescopusMolecular Basis of C-30 Product Regioselectivity of Legume Oxidases Involved in High-Value Triterpenoid Biosynthesis
ArticleAbstract: The triterpenes are structurally diverse group of specialized metabolites with important roles in plPalabras claves:Chemodiversity, cytochrome P450 monooxygenase, Legume, product regioselectivity, triterpeneAutores:Ery Odette Fukushima, Fanani M.Z., Ishimori M., Muranaka T., Ohyama K., Saito K., Sawai S., Seki H., Sudo H., Tang J.Fuentes:googlescopusProduction of the bioactive plant-derived triterpenoid morolic acid in engineered Saccharomyces cerevisiae
ArticleAbstract: Morolic acid is a plant-derived triterpenoid that possesses pharmacological properties such as cytotPalabras claves:GEV chimeric transcription factor, Metabolic engineering, morolic acid, Saccharomyces Cerevisiae, TriterpenoidAutores:Ery Odette Fukushima, Muranaka T., Robertlee J., Seki H., Srisawat P., Yasumoto S.Fuentes:googlescopusPlant cytochrome P450s in triterpenoid biosynthesis: Diversity and application to combinatorial biosynthesis
Book PartAbstract: Plants produce a wide variety of specialized (secondary) metabolites, with which they interact in vaPalabras claves:Coexpression analysis, Glycosyltransferase, Glycyrrhizin, Oxidosqualene, phytochemical, saponin, specialized metabolism, Terpenoid, TriterpenoidAutores:Ery Odette Fukushima, Muranaka T., Seki H.Fuentes:googlescopusβ-amyrin oxidation by oat CYP51H10 expressed heterologously in yeast cells: The first example of CYP51-dependent metabolism other than the 14-demethylation of sterol precursors
ArticleAbstract: CYP51 has been recognized as a unique CYP family that consists of one isolated molecular species, aPalabras claves:CYP51, New function, P450, Sterol 14-demethylation, β-amyrin metabolismAutores:Aoyama Y., Ery Odette Fukushima, Kitahama Y., Kunii M., Muranaka T., Seki H., Yoshida Y.Fuentes:googlescopus