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Combinatorial biosynthesis of legume natural and rare triterpenoids in engineered yeast
ArticleAbstract: Triterpenoid saponins are a diverse group of specialized (secondary) metabolites with many biologicaPalabras claves:4-epi-hederagenin, Combinatorial biosynthesis, CYP72A, cytochrome P450 monooxygenase, Gypsogenic acid, Medicago truncatula, Soyasapogenol BAutores:Ery Odette Fukushima, Muranaka T., Ohyama K., Saito K., Sawai S., Seki H., Suzuki M.Fuentes:googlescopusCYP716A subfamily members are multifunctional oxidases in triterpenoid biosynthesis
ArticleAbstract: Triterpenoids are a diverse group of secondary metabolites that are associated with a variety of bioPalabras claves:CYP716As, Cyt P450 monooxygenase, Medicago truncatula, Triterpenoids, Vitis viníferaAutores:Ery Odette Fukushima, Mizutani M., Muranaka T., Ohyama K., Ono E., Saito K., Seki H., Umemoto N.Fuentes:googlescopusAllylic Hydroxylation Activity Is a Source of Saponin Chemodiversity in the Genus Glycyrrhiza
ArticleAbstract: Licorice (Glycyrrhiza) produces glycyrrhizin, a valuable triterpenoid saponin, which exhibits persisPalabras claves:Allylic hydroxylation, Chemodiversity, CYP88D subfamily, Cytochrome p450, Licorice, TriterpenoidAutores:Ery Odette Fukushima, Fanani M.Z., Ishimori M., Muranaka T., Ohyama K., Saito K., Sawai S., Seki H., Sudo H.Fuentes:googlescopusFunctional analysis of amorpha-4,11-diene synthase (ADS) homologs from non-artemisinin-producing artemisia species: The discovery of novel koidzumiol and (+)-a-Bisabolol synthases
ArticleAbstract: The production of artemisinin, the most effective antimalarial compound, is limited to Artemisia annPalabras claves:(+)-a-Bisabolol, Amorpha-4,11-diene synthase, ARTEMISIA ABSINTHIUM, Artemisia kurramensis, Artemisia maritime, KoidzumiolAutores:Ery Odette Fukushima, Komori A., Mikawa R., Muangphrom P., Muranaka T., Nishiwaki M., Seki H., Suzuki M.Fuentes:googlescopusLotus japonicus Triterpenoid Profile and Characterization of the CYP716A51 and LjCYP93E1 Genes Involved in Their Biosynthesis in Planta
ArticleAbstract: Lotus japonicus is an important model legume plant in several fields of research, such as secondaryPalabras claves:Betulinic acid, CRISPR/Cas9, LORE1, oleanolic acid, Soyasapogenols, Ursolic acidAutores:Ery Odette Fukushima, Fujisawa Y., Ishimoto M., Muranaka T., Osakabe K., Osakabe Y., Seki H., Shimizu Y., Suzuki H.Fuentes:googlescopus