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Bothrops atrox from Ecuadorian Amazon: Initial analyses of venoms from individuals
ArticleAbstract: Bothrops atrox is the most clinically relevant snake species within the Amazon region, which includePalabras claves:antivenom, Enzymatic, Lethality, Phenotype, ToxicologicalAutores:Bruno Mendes, Carolina Proaño-Bolaños, David Salazar-Valenzuela, Evencio Joel Medina-Villamizar, José Rafael de Almeida, Ricardo S.P. Patiño, Saulo L. SilvaFuentes:googlescopusAn experimental protocol for molecular biology lab at an Amazonian University
ArticleAbstract: Laboratory-based practical classes are an essential component in teaching molecular biology for undePalabras claves:frog secretions, laboratory exercise, Molecular cloning, PeptidesAutores:Carolina Proaño-Bolaños, Fernando Valdivieso-Rivera, José Rafael de AlmeidaFuentes:googlescopusCruzioseptins, antibacterial peptides from Cruziohyla calcarifer skin, as promising leishmanicidal agents
ArticleAbstract: Screenings of natural products have significantly contributed to the discovery of novel leishmanicidPalabras claves:Cruzioseptins, Frog skin secretion, Leishmanicidal, PeptidesAutores:Bruno Mendes, Carolina Proaño-Bolaños, Gadelha F.R., José Rafael de Almeida, Miguel D.C.Fuentes:googlescopusDissection of phospholipases A<inf>2</inf> reveals multifaceted peptides targeting cancer cells, Leishmania and bacteria
ArticleAbstract: Cationic peptides bio-inspired by natural toxins have been recognized as an efficient strategy for tPalabras claves:Antimicrobial, Cationic, Cytotoxicity, Leishmanicidal activity, Snake venomAutores:Bruno Mendes, Carolina Proaño-Bolaños, Cristóbal Leonardo Domínguez-Borbor, Edgar A. Pinos-Tamayo, José Rafael de Almeida, Maria S. Peña-Carrillo, Miguel D.C.Fuentes:googlescopusMolecular modeling of four Dermaseptin-related peptides of the gliding tree frog Agalychnis spurrelli
ArticleAbstract: In this research, we present a preliminary computational study of four Dermaseptin-related peptidesPalabras claves:Agalychnis spurrelli, Antimicrobial peptides, Dermaseptins, Molecular dockingAutores:Ailin Blasco-Zuñiga, Carolina Proaño-Bolaños, Felipe E. Gallegos, Fernanda Pilaquinga F．, Josefa Arias, Lorena Maribel Meneses-Olmedo, Lorena Meneses, Miryan Rivera, Sebastian CuestaFuentes:googlescopusNovel Kazal-type proteinase inhibitors from the skin secretion of the Splendid leaf frog, Cruziohyla calcarifer
ArticleAbstract: Peptidase inhibitors have an important role controlling a variety of biological processes. Here, wePalabras claves:Cruziohyla calcarifer, Frog skin secretion, Kazal-type proteinase inhibitors, Molecular cloning, Peptidomic, tandem mass spectrometryAutores:Carolina Proaño-Bolaños, Chen T., Li R., Luis A. Coloma, Shaw C., Tapia E.E., Wang L., Xi X., Zhou M.Fuentes:googlescopusNovel antimicrobial cruzioseptin peptides extracted from the splendid leaf frog, Cruziohyla calcarifer
ArticleAbstract: Antimicrobial peptides (AMPs) constitute part of a broad range of bioactive compounds present on divPalabras claves:Amphibians skin secretion, Antimicrobial peptides, Cruziohyla calcarifer, Cruzioseptins, Molecular cloning, Molecular dockingAutores:Ailin Blasco-Zuñiga, Camila Reinoso, Carolina Proaño-Bolaños, Felipe Morales, Fernanda Pilaquinga F．, Giovanna Morán-Marcillo, Lorena Maribel Meneses-Olmedo, Lorena Meneses, Miryan Rivera, Sebastian CuestaFuentes:googlescopusInspiration from cruzioseptin-1: membranolytic analogue with improved antibacterial properties
ArticleAbstract: Peptide engineering has gained attraction as a source of new cationicity-enhanced analogues with higPalabras claves:Antimicrobial peptides, Cruzioseptin, Membranolytic effect, Rational designAutores:Carolina Proaño-Bolaños, Espinosa de los Monteros-Silva N., Fernanda Toscano, Giovanna Morán-Marcillo, José Rafael de Almeida, Karla Sofía Vizuete Armendáriz, Karla Vizuete, marbel torres arias, Naranjo R.E., Sebastián Bermúdez-PugaFuentes:googlescopusPeptidomic approach identifies cruzioseptins, a new family of potent antimicrobial peptides in the splendid leaf frog, Cruziohyla calcarifer
ArticleAbstract: Phyllomedusine frogs are an extraordinary source of biologically active peptides. At least 8 familiePalabras claves:Antimicrobial peptides, Cruzioseptins, Molecular cloning, Peptidomic, Skin secretions, tandem mass spectrometryAutores:Carolina Proaño-Bolaños, Chen T., Luis A. Coloma, Shaw C., Wang L., Zhou M.Fuentes:googlescopusUnexpected distribution of the fluoroquinolone-resistance gene qnrB in Escherichia coli isolates from different human and poultry origins in Ecuador
ArticleAbstract: Fluoroquinolone resistance can be conferred through chromosomal mutations or by the acquisition of pPalabras claves:ESCHERICHIA coli, Gene qnrB, Industral poultry operations, Quinolone resistance, Urban hospitalsAutores:Carl F. Marrs, Carolina Proaño-Bolaños, Gabriel Trueba, Joseph Neil Spindel Eisenberg, Levy K., Lixin Zhang, Paulina Isabel Armas-Freire, William T. CevallosFuentes:googlescopus