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Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology(3)
Bioorganic Chemistry(1)
Current Issues in Molecular Biology(1)
Drug Development Research(1)
European Journal of Medicinal Chemistry(1)
Assessing the stability of historical and desiccated snake venoms from a medically important Ecuadorian collection
ArticleAbstract: Bothrops asper and Bothrops atrox are important venomous snakes from Ecuador responsible for the mosPalabras claves:Desiccated venom, Proteomic, Snake venom, stability, ToxicologicalAutores:Bruno Mendes, Caldeira C.A.S., Fausto Zaruma-Torres, José Rafael de Almeida, Laines J., Noroska Gabriela Salazar Mogollón, Pico J., Ricardo S.P. Patiño, Saulo L. Silva, Terán M.Fuentes:googlescopusBothrops atrox from Ecuadorian Amazon: Initial analyses of venoms from individuals
ArticleAbstract: Bothrops atrox is the most clinically relevant snake species within the Amazon region, which includePalabras claves:antivenom, Enzymatic, Lethality, Phenotype, ToxicologicalAutores:Bruno Mendes, Carolina Proaño-Bolaños, David Salazar-Valenzuela, Evencio Joel Medina-Villamizar, José Rafael de Almeida, Ricardo S.P. Patiño, Saulo L. SilvaFuentes:googlescopusA novel synthetic peptide inspired on Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
ArticleAbstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics aPalabras claves:Antibacterial activity, Biomimetic peptide, Phospholipase A 2, Snake venomAutores:Bruno Mendes, Fernandes P.A., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Marangoni S., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopusCruzioseptins, antibacterial peptides from Cruziohyla calcarifer skin, as promising leishmanicidal agents
ArticleAbstract: Screenings of natural products have significantly contributed to the discovery of novel leishmanicidPalabras claves:Cruzioseptins, Frog skin secretion, Leishmanicidal, PeptidesAutores:Bruno Mendes, Carolina Proaño-Bolaños, Gadelha F.R., José Rafael de Almeida, Miguel D.C.Fuentes:googlescopusCausative Agents of American Tegumentary Leishmaniasis Are Able to Infect 3T3-L1 Adipocytes In Vitro
ArticleAbstract: Although macrophages have long been considered key players in the course of Leishmania infections, oPalabras claves:3T3-L1, adipocyte, infection, LEISHMANIA, MicroscopyAutores:Andrews N.W., Bruno Mendes, Consonni S.R., Miguel D.C., Minori K.Fuentes:scopusDissection of phospholipases A<inf>2</inf> reveals multifaceted peptides targeting cancer cells, Leishmania and bacteria
ArticleAbstract: Cationic peptides bio-inspired by natural toxins have been recognized as an efficient strategy for tPalabras claves:Antimicrobial, Cationic, Cytotoxicity, Leishmanicidal activity, Snake venomAutores:Bruno Mendes, Carolina Proaño-Bolaños, Cristóbal Leonardo Domínguez-Borbor, Edgar A. Pinos-Tamayo, José Rafael de Almeida, Maria S. Peña-Carrillo, Miguel D.C.Fuentes:googlescopusHarnessing snake venom phospholipases A <inf>2</inf> to novel approaches for overcoming antibiotic resistance
ReviewAbstract: The emergence of antibiotic resistance drives an essential race against time to reveal new molecularPalabras claves:antibacterial peptides, antibiotic-resistant bacteria, Peptidomimetics, Phospholipase A 2, Snake venomAutores:Antonio L.V. Palacios, Bruno Mendes, Gomes P.A.D.C., José Rafael de Almeida, Ricardo S.P. Patiño, Saulo L. Silva, Teixeira C.A.S.Fuentes:googlescopusIn vitro effects of Crotalus atrox snake venom on chick and mouse neuromuscular preparations
ArticleAbstract: The neuromuscular effect of venoms is not a major clinical manifestation shared between rattlesnakesPalabras claves:Crotalus atrox, Myotoxicity, Neuromuscular blockade, Snake venomAutores:Bruno Mendes, Carregari V.C., Hyslop S., José Rafael de Almeida, Noroska Gabriela Salazar Mogollón, Pereira B.B., Santa Fé Miguel A.T., Saulo L. Silva, Schezaro-Ramos R.Fuentes:scopusPeptides to tackle leishmaniasis: Current status and future directions
ReviewAbstract: Peptide-based drugs are an attractive class of therapeutic agents, recently recognized by the pharmaPalabras claves:Amastigote, Drug Discovery, Leishmania spp, Peptides, PromastigoteAutores:Alberto A. Robles-Loaiza, Alejandro Pinos-Tamayo, Alves C., Bruno Mendes, Edgar A. Pinos-Tamayo, Gomes P.A.D.C., José Rafael de Almeida, Teixeira C.A.S.Fuentes:googlescopusLessons from a Single Amino Acid Substitution: Anticancer and Antibacterial Properties of Two Phospholipase A<inf>2</inf>-Derived Peptides
ArticleAbstract: The membrane-active nature of phospholipase A2-derived peptides makes them potential candidates forPalabras claves:Agkistrodon, leucine, Membrane, Phenylalanine, Venom peptidesAutores:Alves C., Bruno Mendes, Fernandes P.A., Franchi G.C., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopus