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CoaTx-II, a new dimeric Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles
ArticleAbstract: Snake venoms are rich and intriguing sources of biologically-active molecules that act on target celPalabras claves:Antibacterial effect, Crotalus oreganus abyssus, Lys49 phospholipase A 2, Myotoxicity, Snake venomAutores:de Azevedo Calderon L., González W., José Rafael de Almeida, Lancellotti M., Marangoni S., Ramírez D., Saulo L. Silva, Soares A.M.Fuentes:googlescopusBiochemical and functional studies of ColTx-I, a new myotoxic phospholipase A<inf>2</inf> isolated from Crotalus oreganus lutosus (Great Basin rattlesnake) snake venom
ArticleAbstract: Commonly, phospholipases A2 (PLA2s) play key roles in the pathogenesis of the local tissue damage chPalabras claves:Biological activities, Crotalus oreganus lutosus, Myotoxin, Phospholipase A 2, Snake venomAutores:de Azevedo Calderon L., José Rafael de Almeida, Marangoni S., Resende L.M., Ribeiro R.I.M.A., Saulo L. Silva, Silva A.G., Soares A.M., Stábeli R.G.Fuentes:scopusA novel synthetic peptide inspired on Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
ArticleAbstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics aPalabras claves:Antibacterial activity, Biomimetic peptide, Phospholipase A 2, Snake venomAutores:Bruno Mendes, Fernandes P.A., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Marangoni S., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopusGenetic and phenotypic diversity of Rhizobium isolates from southern Ecuador
ArticleAbstract: Rhizobium-legume symbioses play relevant roles in agriculture but have not been well studied in EcuaPalabras claves:16S rRNA gene, Diazotrophic bacteria, Indole acetic acid, Nodulation, Phaseolus vulgarisAutores:Alvarado-Capó Y., Aminael Sánchez-Rodríguez, José Rafael de Almeida, Klever Iván Granda-Mora, Noroska Gabriela Salazar Mogollón, Roldán Torres GutiérrezFuentes:scopusExploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A<inf>2,</inf> AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom
ArticleAbstract: Phospholipases A2 (PLA2s) constitute a class of extensively studied toxins, isolated from snake venoPalabras claves:Acidic phospholipase A 2, Agkistrodon piscivorus leucostoma, Pharmacological activity, Snake venomAutores:Collaço R.C.O., de Azevedo Calderon L., González W., José Rafael de Almeida, Marangoni S., Ramírez D., Resende L.M., Saulo L. Silva, Schezaro-Ramos R., Simioni L.R., Soares A.M.Fuentes:scopusIsolation and characterization of a natriuretic peptide from crotalus oreganus abyssus (grand canyon rattlesnake) and its effects on systemic blood pressure and nitrite levels
ArticleAbstract: Studies on the therapeutic potential of venom peptides have significantly advanced the development oPalabras claves:Bioactive peptides, Crotalus oreganus abyssus, Natriuretic peptide, Nitric oxideAutores:Baldasso P.A., Dias-Junior C.A., Henriques F.A.F.A., José Rafael de Almeida, Marangoni S., Martins W., Resende L.M., Resende R.R., Saulo L. Silva, Soares A.M., Taranto A.G.Fuentes:scopusSnake venom PLA<inf>2</inf>s inhibitors isolated from brazilian plants: Synthetic and natural molecules
ReviewAbstract: Ophidian envenomation is an important health problem in Brazil and other South American countries. IPalabras claves:Autores:Carvalho B.M.A., de Azevedo Calderon L., José Rafael de Almeida, Marangoni S., Marchi-Salvador D.P., Marcussi S., Martins W., Resende L.M., Santos J.D.L., Saulo L. Silva, Soares A.M., Stábeli R.G., Xavier B.M.Fuentes:scopusStructural, enzymatic and pharmacological profiles of AplTX-II - A basic sPLA<inf>2</inf> (D49) isolated from the Agkistrodon piscivorus leucostoma snake venom
ArticleAbstract: A basic sPLA2 (D49) from the venom of snake Agkistrodon piscivorus leucostoma (AplTX-II) was isolatePalabras claves:Agkistrodon piscivorus leuscostoma, Basic sPLA D49 2, molecular modeling, NOBA (4-nitro-3-octanoyloxy benzoic acid)Autores:Fernandes P.A., José Rafael de Almeida, Marangoni S., Ramos M.J., Resende L.M., Saulo L. Silva, Soares A.M., Tatiana A. Guaraca-Medina, Viegas M.F.Fuentes:scopus