Mostrando 10 resultados de: 11
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Toxicon(4)
Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology(1)
Current Issues in Molecular Biology(1)
International Journal of Biological Macromolecules(1)
International Journal of Molecular Sciences(1)
Anti-platelet aggregation activity of two novel acidic Asp49-phospholipases A<inf>2</inf> from Bothrops brazili snake venom
ArticleAbstract: Phospholipases A2 (PLA2s) are important enzymes present in snake venoms and are related to a wide spPalabras claves:Acidic phospholipases A 2, Anti-platelet aggregation activity, Bothrops brazili, Snake venomAutores:Alfonso J.J., Fuly A.L., Gómez A.F., Gomez M.C.V., José Rafael de Almeida, Kayano A.M., Moura L.A., Oliveira E., Saulo L. Silva, Simões-Silva R., Soares A.M., Sobrinho J.C., Souza V.R., Zanchi F.B., Zuliani J.P.Fuentes:googlescopusCorrigendum to “Exploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A2, AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom” [Toxicon 127 (2017) 22–36] (S004101011730003X) (10.1016/j.toxicon.2017.01.002)
OtherAbstract: 2.5.2. Homology modeling and molecular dynamic studies The homology model of AplTx-I were built (usiPalabras claves:Autores:Collaço R.C.O., de Azevedo Calderon L., González W., José Rafael de Almeida, Marangoni S., Ramírez D., Ramos R.S., Resende L.M., Saulo L. Silva, Simioni L.R., Soares A.M.Fuentes:scopusCruzioseptins, antibacterial peptides from Cruziohyla calcarifer skin, as promising leishmanicidal agents
ArticleAbstract: Screenings of natural products have significantly contributed to the discovery of novel leishmanicidPalabras claves:Cruzioseptins, Frog skin secretion, Leishmanicidal, PeptidesAutores:Bruno Mendes, Carolina Proaño-Bolaños, Gadelha F.R., José Rafael de Almeida, Miguel D.C.Fuentes:googlescopusDeciphering the Limitations and Antibacterial Mechanism of Cruzioseptins
ArticleAbstract: Antimicrobial peptides consist mainly of membrane-active sequences, which are potentially relevant tPalabras claves:Antimicrobial, Membranolytic, Peptides, Physiological conditionAutores:Carolina Proaño-Bolaños, Fernando Valdivieso-Rivera, José Rafael de Almeida, Sebastián Bermúdez-PugaFuentes:scopusNeutrophil-mediated erythrophagocytosis following Russell's viper (Daboia russelii) bite
ArticleAbstract: Snakebite envenomation is regarded as a high-priority neglected tropical disease by the World HealthPalabras claves:Daboia russelii, Erythrophagocytosis, neutrophils, Peripheral blood smear, Russell's viper, Snakebite envenomationAutores:Arathisenthil S.V., José Rafael de Almeida, Patel K., Rajan E., Senthilkumaran S., Thirumalaikolundusubramanian P., Vaiyapuri S., Williams H.F., Williams J.Fuentes:googlescopusPeptides to tackle leishmaniasis: Current status and future directions
ReviewAbstract: Peptide-based drugs are an attractive class of therapeutic agents, recently recognized by the pharmaPalabras claves:Amastigote, Drug Discovery, Leishmania spp, Peptides, PromastigoteAutores:Alberto A. Robles-Loaiza, Alejandro Pinos-Tamayo, Alves C., Bruno Mendes, Edgar A. Pinos-Tamayo, Gomes P.A.D.C., José Rafael de Almeida, Teixeira C.A.S.Fuentes:googlescopusLessons from a Single Amino Acid Substitution: Anticancer and Antibacterial Properties of Two Phospholipase A<inf>2</inf>-Derived Peptides
ArticleAbstract: The membrane-active nature of phospholipase A2-derived peptides makes them potential candidates forPalabras claves:Agkistrodon, leucine, Membrane, Phenylalanine, Venom peptidesAutores:Alves C., Bruno Mendes, Fernandes P.A., Franchi G.C., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopusIsolation, structural and functional characterization of a new Lys49 phospholipase A<inf>2</inf> homologue from Bothrops neuwiedi urutu with bactericidal potential
ArticleAbstract: Snake venom is a complex mixture of active compounds consisting of 80-90% proteins and peptides thatPalabras claves:bactericidal activity, Bothrops neuwiedi, Phospholipase A 2, Snake venomAutores:Corrêa E.A., de Azevedo Calderon L., Diniz-Sousa R., José Rafael de Almeida, Kayano A.M., Marangoni S., Matos N.B., Resende L.M., Saulo L. Silva, Setúbal S.S., Soares A.M., Zanchi F.B., Zuliani J.P.Fuentes:googlescopusRapid identification of bilateral adrenal and pituitary haemorrhages induced by Russell's viper envenomation results in positive patient outcome
ArticleAbstract: The clinical management of snakebite envenomation (SBE) is challenging in many tropical and subtropiPalabras claves:Acute haemorrhage, Adrenal haemorrhage, Dexamethasone, Pituitary haemorrhage, Russell's viper, Snakebite envenomationAutores:José Rafael de Almeida, Patel K., Senthilkumaran S., Thirumalaikolundusubramanian P., Vaiyapuri S., Williams H.F., Williams J.Fuentes:googlescopusPotential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents
ArticleAbstract: Phospholipase A2 toxins present in snake venoms interact with biological membranes and serve as struPalabras claves:Leishmanicidal activity, Oligoarginine, peptide, PhospholipaseAutores:Bruno Mendes, Gadelha F.R., Gomes P.A.D.C., José Rafael de Almeida, Miguel D.C., Saulo L. Silva, Vale N.Fuentes:scopus