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Toxicon(5)
Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology(2)
International Journal of Biological Macromolecules(2)
Toxins(2)
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A First Look at the Inhibitory Potential of Urospatha sagittifolia (Araceae) Ethanolic Extract for Bothrops atrox Snakebite Envenomation
ArticleAbstract: Bothrops atrox snakebites are a relevant problem in the Amazon basin. In this biodiverse region, thePalabras claves:AMAZON, antivenom, Araceae, Enzymes, plants, snakebite, ToxinsAutores:Andres Moreno, Antonio L. Vera-Palacios, David Salazar-Valenzuela, José Rafael de Almeida, Josselin A. Hernández-Altamirano, Juan D. Sacoto-Torres, María Cristina Peñuela Mora, Noroska Gabriela Salazar MogollónFuentes:scopusA novel synthetic peptide inspired on Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
ArticleAbstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics aPalabras claves:Antibacterial activity, Biomimetic peptide, Phospholipase A 2, Snake venomAutores:Bruno Mendes, Fernandes P.A., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Marangoni S., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopusCoaTx-II, a new dimeric Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles
ArticleAbstract: Snake venoms are rich and intriguing sources of biologically-active molecules that act on target celPalabras claves:Antibacterial effect, Crotalus oreganus abyssus, Lys49 phospholipase A 2, Myotoxicity, Snake venomAutores:de Azevedo Calderon L., González W., José Rafael de Almeida, Lancellotti M., Marangoni S., Ramírez D., Saulo L. Silva, Soares A.M.Fuentes:googlescopusBiochemical and functional studies of ColTx-I, a new myotoxic phospholipase A<inf>2</inf> isolated from Crotalus oreganus lutosus (Great Basin rattlesnake) snake venom
ArticleAbstract: Commonly, phospholipases A2 (PLA2s) play key roles in the pathogenesis of the local tissue damage chPalabras claves:Biological activities, Crotalus oreganus lutosus, Myotoxin, Phospholipase A 2, Snake venomAutores:de Azevedo Calderon L., José Rafael de Almeida, Marangoni S., Resende L.M., Ribeiro R.I.M.A., Saulo L. Silva, Silva A.G., Soares A.M., Stábeli R.G.Fuentes:scopusAnti-platelet aggregation activity of two novel acidic Asp49-phospholipases A<inf>2</inf> from Bothrops brazili snake venom
ArticleAbstract: Phospholipases A2 (PLA2s) are important enzymes present in snake venoms and are related to a wide spPalabras claves:Acidic phospholipases A 2, Anti-platelet aggregation activity, Bothrops brazili, Snake venomAutores:Alfonso J.J., Fuly A.L., Gómez A.F., Gomez M.C.V., José Rafael de Almeida, Kayano A.M., Moura L.A., Oliveira E., Saulo L. Silva, Simões-Silva R., Soares A.M., Sobrinho J.C., Souza V.R., Zanchi F.B., Zuliani J.P.Fuentes:googlescopusCorrigendum to “Exploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A2, AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom” [Toxicon 127 (2017) 22–36] (S004101011730003X) (10.1016/j.toxicon.2017.01.002)
OtherAbstract: 2.5.2. Homology modeling and molecular dynamic studies The homology model of AplTx-I were built (usiPalabras claves:Autores:Collaço R.C.O., de Azevedo Calderon L., González W., José Rafael de Almeida, Marangoni S., Ramírez D., Ramos R.S., Resende L.M., Saulo L. Silva, Simioni L.R., Soares A.M.Fuentes:scopusHarnessing snake venom phospholipases A <inf>2</inf> to novel approaches for overcoming antibiotic resistance
ReviewAbstract: The emergence of antibiotic resistance drives an essential race against time to reveal new molecularPalabras claves:antibacterial peptides, antibiotic-resistant bacteria, Peptidomimetics, Phospholipase A 2, Snake venomAutores:Antonio L.V. Palacios, Bruno Mendes, Gomes P.A.D.C., José Rafael de Almeida, Ricardo S.P. Patiño, Saulo L. Silva, Teixeira C.A.S.Fuentes:googlescopusIn vitro effects of Crotalus atrox snake venom on chick and mouse neuromuscular preparations
ArticleAbstract: The neuromuscular effect of venoms is not a major clinical manifestation shared between rattlesnakesPalabras claves:Crotalus atrox, Myotoxicity, Neuromuscular blockade, Snake venomAutores:Bruno Mendes, Carregari V.C., Hyslop S., José Rafael de Almeida, Noroska Gabriela Salazar Mogollón, Pereira B.B., Santa Fé Miguel A.T., Saulo L. Silva, Schezaro-Ramos R.Fuentes:scopusInspiration from cruzioseptin-1: membranolytic analogue with improved antibacterial properties
ArticleAbstract: Peptide engineering has gained attraction as a source of new cationicity-enhanced analogues with higPalabras claves:Antimicrobial peptides, Cruzioseptin, Membranolytic effect, Rational designAutores:Carolina Proaño-Bolaños, Espinosa de los Monteros-Silva N., Fernanda Toscano, Giovanna Morán-Marcillo, José Rafael de Almeida, Karla Sofía Vizuete Armendáriz, Karla Vizuete, marbel torres arias, Naranjo R.E., Sebastián Bermúdez-PugaFuentes:googlescopusIsolation and characterization of a natriuretic peptide from crotalus oreganus abyssus (grand canyon rattlesnake) and its effects on systemic blood pressure and nitrite levels
ArticleAbstract: Studies on the therapeutic potential of venom peptides have significantly advanced the development oPalabras claves:Bioactive peptides, Crotalus oreganus abyssus, Natriuretic peptide, Nitric oxideAutores:Baldasso P.A., Dias-Junior C.A., Henriques F.A.F.A., José Rafael de Almeida, Marangoni S., Martins W., Resende L.M., Resende R.R., Saulo L. Silva, Soares A.M., Taranto A.G.Fuentes:scopus