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CoaTx-II, a new dimeric Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles
ArticleAbstract: Snake venoms are rich and intriguing sources of biologically-active molecules that act on target celPalabras claves:Antibacterial effect, Crotalus oreganus abyssus, Lys49 phospholipase A 2, Myotoxicity, Snake venomAutores:de Azevedo Calderon L., González W., José Rafael de Almeida, Lancellotti M., Marangoni S., Ramírez D., Saulo L. Silva, Soares A.M.Fuentes:googlescopusBiochemical and functional studies of ColTx-I, a new myotoxic phospholipase A<inf>2</inf> isolated from Crotalus oreganus lutosus (Great Basin rattlesnake) snake venom
ArticleAbstract: Commonly, phospholipases A2 (PLA2s) play key roles in the pathogenesis of the local tissue damage chPalabras claves:Biological activities, Crotalus oreganus lutosus, Myotoxin, Phospholipase A 2, Snake venomAutores:de Azevedo Calderon L., José Rafael de Almeida, Marangoni S., Resende L.M., Ribeiro R.I.M.A., Saulo L. Silva, Silva A.G., Soares A.M., Stábeli R.G.Fuentes:scopusBothrops atrox from Ecuadorian Amazon: Initial analyses of venoms from individuals
ArticleAbstract: Bothrops atrox is the most clinically relevant snake species within the Amazon region, which includePalabras claves:antivenom, Enzymatic, Lethality, Phenotype, ToxicologicalAutores:Bruno Mendes, Carolina Proaño-Bolaños, David Salazar-Valenzuela, Evencio Joel Medina-Villamizar, José Rafael de Almeida, Ricardo S.P. Patiño, Saulo L. SilvaFuentes:googlescopusCorrigendum to “Exploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A2, AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom” [Toxicon 127 (2017) 22–36] (S004101011730003X) (10.1016/j.toxicon.2017.01.002)
OtherAbstract: 2.5.2. Homology modeling and molecular dynamic studies The homology model of AplTx-I were built (usiPalabras claves:Autores:Collaço R.C.O., de Azevedo Calderon L., González W., José Rafael de Almeida, Marangoni S., Ramírez D., Ramos R.S., Resende L.M., Saulo L. Silva, Simioni L.R., Soares A.M.Fuentes:scopusExploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A<inf>2,</inf> AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom
ArticleAbstract: Phospholipases A2 (PLA2s) constitute a class of extensively studied toxins, isolated from snake venoPalabras claves:Acidic phospholipase A 2, Agkistrodon piscivorus leucostoma, Pharmacological activity, Snake venomAutores:Collaço R.C.O., de Azevedo Calderon L., González W., José Rafael de Almeida, Marangoni S., Ramírez D., Resende L.M., Saulo L. Silva, Schezaro-Ramos R., Simioni L.R., Soares A.M.Fuentes:scopusNeutrophil-mediated erythrophagocytosis following Russell's viper (Daboia russelii) bite
ArticleAbstract: Snakebite envenomation is regarded as a high-priority neglected tropical disease by the World HealthPalabras claves:Daboia russelii, Erythrophagocytosis, neutrophils, Peripheral blood smear, Russell's viper, Snakebite envenomationAutores:Arathisenthil S.V., José Rafael de Almeida, Patel K., Rajan E., Senthilkumaran S., Thirumalaikolundusubramanian P., Vaiyapuri S., Williams H.F., Williams J.Fuentes:googlescopusIsolation, structural and functional characterization of a new Lys49 phospholipase A<inf>2</inf> homologue from Bothrops neuwiedi urutu with bactericidal potential
ArticleAbstract: Snake venom is a complex mixture of active compounds consisting of 80-90% proteins and peptides thatPalabras claves:bactericidal activity, Bothrops neuwiedi, Phospholipase A 2, Snake venomAutores:Corrêa E.A., de Azevedo Calderon L., Diniz-Sousa R., José Rafael de Almeida, Kayano A.M., Marangoni S., Matos N.B., Resende L.M., Saulo L. Silva, Setúbal S.S., Soares A.M., Zanchi F.B., Zuliani J.P.Fuentes:googlescopusRapid identification of bilateral adrenal and pituitary haemorrhages induced by Russell's viper envenomation results in positive patient outcome
ArticleAbstract: The clinical management of snakebite envenomation (SBE) is challenging in many tropical and subtropiPalabras claves:Acute haemorrhage, Adrenal haemorrhage, Dexamethasone, Pituitary haemorrhage, Russell's viper, Snakebite envenomationAutores:José Rafael de Almeida, Patel K., Senthilkumaran S., Thirumalaikolundusubramanian P., Vaiyapuri S., Williams H.F., Williams J.Fuentes:googlescopusRussell's viper envenomation induces rectus sheath haematoma
ArticleAbstract: Snakebite envenomation causes systemic and local manifestations, which result from the individual orPalabras claves:Computed tomographic imaging, Daboia russelii, Fothergill and carnett signs, Rectus sheath haematoma, Russell's viper, Snakebite envenomationAutores:José Rafael de Almeida, Patel K., Salim A., Senthilkumaran S., Thirumalaikolundusubramanian P., Vaiyapuri S., Williams H.F., Williams J.Fuentes:googlescopus