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4(1H)-quinolones with liver stage activity against Plasmodium berghei
ArticleAbstract: With the exception of primaquine, tafenoquine, and atovaquone, there are very few antimalarials thatPalabras claves:Autores:Cross R.M., Fabián E. Sáenz, Kyle D.E., Lacrue A.N., Manetsch R., Monastyrskyi A., Mutka T.S., Stein S., Udenze K.O.Fuentes:googlescopus4-(1H)-quinolones and 1,2,3,4-tetrahydroacridin-9(10H)-ones prevent the transmission of Plasmodium falciparum to Anopheles freeborni
ArticleAbstract: Malaria kills approximately 1 million people a year, mainly in sub-Saharan Africa. Essential steps iPalabras claves:Autores:Cross R.M., Fabián E. Sáenz, Kyle D.E., Lacrue A.N., Maignan J.R., Manetsch R., Udenze K.O.Fuentes:googlescopusClonal population expansion in an outbreak of Plasmodium falciparum on the northwest coast of Ecuador
ArticleAbstract: Background: Determining the source of malaria outbreaks in Ecuador and identifying remaining transmiPalabras claves:ECUADOR, MALARIA, Microsatellite markers, Outbreak, Plasmodium falciparumAutores:Castro L.E., Claudia A. Vera-Arias, Eileen Vélez-Álvarez, Fabián E. Sáenz, Gabriela Valenzuela, Lucchi N.W., Morton L.C., Okoth S.A., Udhayakumar V.Fuentes:scopusAnopheline and human drivers of malaria risk in northern coastal, Ecuador: A pilot study
ArticleAbstract: Background: Understanding local anopheline vector species and their bionomic traits, as well as relaPalabras claves:Anopheles calderoni, Bionomics, ECUADOR, Human behaviour, Indoor residual spraying (IRS), Long-lasting insecticide-treated nets (LLINs), MALARIA, Nyssorhynchus albimanus, Plasmodium falciparumAutores:Bibiana E. Salazar-Costa, Claudia A. Vera-Arias, English D.J., Fabián E. Sáenz, Hendershot A.L., Iván Alejandro Saá Portilla, Juan José Bustillos, Koepfli C., Lobo N.F., Martin J.A., Sofia Ocana-Mayorga, Woodruff M.Fuentes:scopusDiverse origin of Plasmodium falciparum in northwest Ecuador
ArticleAbstract: Background: Ecuador plans to eliminate malaria by 2020, and the country has already seen a decreasePalabras claves:ECUADOR, Genetic structure, MALARIA, microsatellites, Plasmodium falciparumAutores:Castro L.E., Claudia A. Vera-Arias, Fabián E. Sáenz, Gómez-Obando J.Fuentes:googlescopusGenotypes and phenotypes of resistance in Ecuadorian Plasmodium falciparum
ArticleAbstract: Background: Malaria continues to be endemic in the coast and Amazon regions of Ecuador. Clarifying cPalabras claves:ECUADOR, Genotypes, MALARIA, Phenotypes, Plasmodium falciparum, RESISTANCEAutores:Castro L.E., Claudia A. Vera-Arias, Fabián E. Sáenz, Gabriela Valenzuela, Rohrbach P., Valencia-Zamora J.Fuentes:googlescopusHigh-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy
ArticleAbstract: Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich Proteins 2 aPalabras claves:Autores:Abdul-Hakim M., Afrane Y., Ali A., Badu K., Claudia A. Vera-Arias, Fabián E. Sáenz, Fakih B.S., Ferreira M.U., Hetzel M.W., Holzschuh A., Kazura J.W., Koepfli C., Ladeia-Andrade S., Oduma C.O., Yan G., Yewhalaw D., Yukich J., Zemene E.Fuentes:googlescopusEvidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model
ArticleAbstract: The increasing prevalence in Southeast Asia of Plasmodium falciparum infections with delayed parasitPalabras claves:Autores:Cremers S., Fabián E. Sáenz, Fidock D.A., Henrich P.P., Kyle D.E., O'Brien C.Fuentes:googlescopusLamina-associated polypeptide 2 (LAP2) expression in fish and amphibians
ArticleAbstract: Somatic and germinal cells of 15 fish and 33 amphibian species were examined by SDS-PAGE followed byPalabras claves:Germ cell, LAP2, Somatic cell, Xenopus, zebrafishAutores:Ávila M.E., Eugenia M. del Pino, Fabián E. Sáenz, Federico Brown, Haddad N., Krohne G., Oscar D. Pérez, Paulin-Levasseur M., Verónica BarragánFuentes:scopusQuinolone-3-diarylethers: A new class of antimalarial drug
ArticleAbstract: The goal for developing new antimalarial drugs is to find a molecule that can target multiple stagesPalabras claves:Autores:Angulo-Barturen I., Avery V.M., Bathurst I., Burrows J.N., Charman S.A., Cross R.M., Delves M.J., Duffy S., Fabián E. Sáenz, Ferrer S., Forquer I.P., Gamo F.J., Guy R.K., Herreros E., Jiménez-Díaz M.B., Kelly J.X., Kocken C.H.M., Kyle D.E., Lacrue A.N., Li Y., Manetsch R., Marfurt J., Mather M.W., Morrisey J.M., Mutka T.S., Nilsen A., Noviyanti R., Price R.N., Riscoe M.K., Ryan E., Sanz L.M., Sebayang B.F., Shackleford D.M., Siegl P., Sinden R.E., Steuten J., Vaidya A.B., White K.L., Winter R.W., Wirjanata G., Zeeman A.M.Fuentes:googlescopus