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scopus(23)
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
ArticleAbstract: Pyrin responds to pathogen signals and loss of cellular homeostasis by forming an inflammasome complPalabras claves:Autores:Amselem S., Baker P.J., Cochet E., Copin B., Dagley L.F., De Nardo D., De Somer L., Dooley J., Goris A., Holley C.L., Jeandel P.Y., Jéru I., Josselyn E. Garcia-Perez, Lagou V., Lawless D., Liston A., Lyras D., Masters S.L., Medlej-Hashim M., Megarbane A., Moghaddas F., Nicholson S.E., Parry D.A., Pasciuto E., Ruuth-Praz J., Savic S., Schroder K., Sciot R., Van Eyck L., Van Nieuwenhove E., Webb A.I., Wouters C.H.Fuentes:scopusExosome Isolation by Ultracentrifugation and Precipitation and Techniques for Downstream Analyses
ArticleAbstract: Exosomes are 50- to 150-nm-diameter extracellular vesicles secreted by all mammalian cells except maPalabras claves:exosome, Isolation, Lipoproteins, Mass spectrometry, ultracentrifugationAutores:Adame V., Anton P., Bettcher B.M., Boyd T.D., Bruce K.D., Burgy O., Chial H.J., Coughlan C., Graner M., Hsieh E.W.Y., Josselyn E. Garcia-Perez, Königshoff M., Michel C.R., Potter H.Fuentes:scopusGenetic Architecture of Adaptive Immune System Identifies Key Immune Regulators
ArticleAbstract: The immune system is highly diverse, but characterization of its genetic architecture has lagged behPalabras claves:adaptive immune system, association, autoimmunity, Genetics, Genome-wide association, immune phenotype, susceptibilityAutores:Boeckxstaens G., Bowness P., Chen L., Dooley J., Dubois B., Goris A., Hilven K., Humblet-Baron S., Josselyn E. Garcia-Perez, Lagou V., Liston A., Mallants K., Moisse M., Prezzemolo T., Smets I., Van Damme P., Van Horebeek L., Vandebergh M.Fuentes:scopusGenetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes
ArticleAbstract: Type 1 (T1D) and type 2 (T2D) diabetes share pathophysiological characteristics, yet mechanistic linPalabras claves:Autores:Allemeersch J., Carr E.J., Chabot-Roy G., Dahlstrom J.E., Delghingaro-Augusto V., Di Marino D., Dooley J., Franckaert D., Gevaert K., Goodnow C.C., Jetten A.M., Josselyn E. Garcia-Perez, Lagou V., Lambrechts D., Laybutt D.R., Lesage S., Linterman M.A., Liston A., Lyssenko V., Nolan C.J., Oskolkov N., Overbergh L., Pasciuto E., Petrovsky N., Schlenner S.M., Schönefeldt S., Socha L., Tian L., Vandenbussche J.Fuentes:scopusCorrection: A novel human IL2RB mutation results in T and NK cell–driven immune dysregulation (CMAJ (2019) 216, 6 (1255) DOI: 10.1084/jem.20182015)
OtherAbstract: The authors regret that in the original version of Fig. S2 G, the plot for healthy pediatric (H. PedPalabras claves:Autores:Baxter R.M., Black J., Blish C.A., Dawany N., de Zoeten E.F., Dutmer C.M., Eissa H., Fernandez I.Z., Galambos C., Gumbart J.C., Hsieh E.W.Y., Josselyn E. Garcia-Perez, Kedl R.M., Kelsen J.R., Kong D.S., Lundquist K., Nguyen T., Ogolla S., Quinones R., Ranganath T., Rochford R., Sullivan K.E., Vendrame E., Verneris M.R.Fuentes:scopusCytotoxic T-lymphocyte-associated protein 4-Ig effectively controls immune activation and inflammatory disease in a novel murine model of leaky severe combined immunodeficiency
ArticleAbstract: Background: Severe combined immunodeficiency can be caused by loss-of-function mutations in genes inPalabras claves:Artemis, cytotoxic T-lymphocyte-associated protein 4, immune dysregulation, Leaky severe combined immunodeficiency, regulatory T cellAutores:Baron F., Humblet-Baron S., Josselyn E. Garcia-Perez, Liston A., Pasciuto E., Schönefeldt S.Fuentes:scopusA framework for understanding the evasion of host immunity by Candida biofilms
OtherAbstract: Candida biofilms are a major cause of nosocomial morbidity and mortality. The mechanism by which CanPalabras claves:BIOFILMS, Candida, cytokines, Immune resistance, Trained immunityAutores:Braem A., Humblet-Baron S., Josselyn E. Garcia-Perez, Lagrou K., Liston A., Mathé L., Van Dijck P.Fuentes:scopusA kindred with mutant IKAROS and autoimmunity
ArticleAbstract:Palabras claves:Autores:Claessens F., Dooley J., Frietze S., Gijsbers R., Helsen C., Humblet-Baron S., Josselyn E. Garcia-Perez, Liston A., Meyts I., Rodriguez P.D., Schjerven H., Schlenner S.M., van der Burg M., Van Nieuwenhove E., van Schouwenburg P.A., Verhoeyen E., Wouters C.H.Fuentes:scopusA novel human IL2RB mutation results in T and NK cell–driven immune dysregulation
ArticleAbstract: The pleiotropic actions of interleukin-2 (IL-2) are essential for regulation of immune responses andPalabras claves:Autores:Baxter R.M., Black J., Blish C.A., Dawany N., de Zoeten E.F., Dutmer C.M., Eissa H., Fernandez I.Z., Galambos C., Gumbart J.C., Hsieh E.W.Y., Josselyn E. Garcia-Perez, Kedl R.M., Kelsen J.R., Kong D.S., Lundquist K., Nguyen T., Ogolla S., Quinones R., Ranganath T., Rochford R., Sullivan K.E., Vendrame E., Verneris M.R.Fuentes:scopusChagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit i (TcI<inf>DOM</inf>)
ArticleAbstract: Background: Trypanosoma cruzi, causative agent of Chagas disease, displays high intraspecific genetiPalabras claves:Chagas disease, Chagasic cardiomyopathy, Lineage, reactivation, TRYPANOSOMA CRUZIAutores:Andrea Cristina Zurita-Leal, Bhattacharyya T., Burleigh B.A., Jaime Alfredo Costales, Josselyn E. Garcia-Perez, Kotton C.N., Llewellyn M.S., Messenger L.A.Fuentes:scopus