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An analysis of preclinical efficacy testing of antivenoms for sub-Saharan Africa: Inadequate independent scrutiny and poor-quality reporting are barriers to improving snakebite treatment and management
ArticleAbstract: Background The World Health Organization’s strategy to halve snakebite mortality and morbidity by 20Palabras claves:Autores:Ainsworth S., Casewell N.R., Harrison R.A., Stefanie K. MenziesFuentes:scopusNon-natural Acetogenin Analogues as Potent Trypanosoma brucei Inhibitors
ArticleAbstract: Neglected tropical diseases remain a serious global health concern. Here, a series of novel bis-tetrPalabras claves:acetogenin, Human African Trypanosomiasis (HAT), natural product analogues, Neglected diseases, stereochemistry, Trypanosoma bruceiAutores:Florence G.J., Fraser A.L., Gould E.R., King E.F.B., Morris J.C., Smith T.K., Stefanie K. Menzies, Tulloch L.B.Fuentes:scopusIn vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus
ArticleAbstract: Snakebite envenoming affects more than 250,000 people annually in sub-Saharan Africa. Envenoming byPalabras claves:Boomslang, drugs, Small molecules, snakebite, SVMPAutores:Alsolaiss J., Casewell N.R., Clare R.H., Crittenden E., Edge R.J., Hall S.R., Harrison R.A., Kool J., Marriott A.E., Stefanie K. Menzies, Westhorpe A., Xie C.Fuentes:scopusLivestock herding and fulani ethnicity are a combined risk factor for development of early adverse reactions to antivenom treatment: Findings from a cross-sectional study in Nigeria
ArticleAbstract: Background Adverse reactions to antivenom considerably complicate the clinical management of snakebiPalabras claves:Autores:Abubakar S.B., Durfa N., Habib A.G., Harrison R.A., Lalloo D.G., Nasidi A., Patel R., Stefanie K. Menzies, Thomas A.O., Tianyi F.L., Trelfa A.Fuentes:scopusTwo snakebite antivenoms have potential to reduce Eswatini’s dependency upon a single, increasingly unavailable product: Results of preclinical efficacy testing
ArticleAbstract: Background Snakebite is a major public health concern in Eswatini, where treatment relies upon one aPalabras claves:Autores:Alsolaiss J., Casewell N.R., Crittenden E., Edge R.J., Hall S.R., Harrison R.A., Lalloo D.G., Litschka-Koen T., Murray J., Padidar S., Pons J., Shongwe N., Stefanie K. Menzies, Thomas B., Westhorpe A.Fuentes:scopusRisk Factors for Soil-Transmitted Helminth Infections during the First 3 Years of Life in the Tropics; Findings from a Birth Cohort
ArticleAbstract: Background:Soil-transmitted helminths (STH) infect more than 2 billion humans worldwide, causing sigPalabras claves:Autores:Alejandro Rodriguez, Carlos A. Sandoval, Guadalupe I., Martha E. Chico, Nely Broncano, Philip John Cooper, Stefanie K. MenziesFuentes:scopus