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Enhancing MicroRNA Activity through Increased Endosomal Release Mediated by Nigericin
ArticleAbstract: The therapeutic promise of small-RNA therapeutics is limited, not only by the lack of delivery vehicPalabras claves:DELIVERY, endosomal escape, folate, folate-conjugates, ligand, microRNA, miR-34, nigericinAutores:Abdelaal A.M., Esteban A. Orellana, Kasinski A.L., Low P.S., Myoung S., Rangasamy L., Tenneti S.Fuentes:scopusMETTL4 is an snRNA m<sup>6</sup>Am methyltransferase that regulates RNA splicing
OtherAbstract:Palabras claves:Autores:Chen H., Esteban A. Orellana, Gregory R.I., Gu L., Guo J., Liu Q., Shen Z., Shi Y., Wang L., Wang Y., Wu H., Xing Y.Fuentes:scopusIdentification and validation of microRNAs that synergize with miR-34a–a basis for combinatorial microRNA therapeutics
ArticleAbstract: Efforts to search for better treatment options for cancer have been a priority, and due to these effPalabras claves:combinatorial therapeutics, miR-34, miR-34a, miRNA therapeutics, Mirna-34, synergismAutores:Esteban A. Orellana, Kasinski A.L., Li C., Lisevick A.Fuentes:scopustRNA dysregulation and disease
ReviewAbstract: tRNAs are key adaptor molecules that decipher the genetic code during translation of mRNAs in proteiPalabras claves:Autores:Esteban A. Orellana, Gregory R.I., Siegal E.Fuentes:scopus