Documentos de Esteban A. Orellana | REDI

Regresar

Mostrando 5 resultados de: 5

Filtros aplicados

Área de conocimiento: "Cáncer"

Subtipo de publicación

Publisher

Molecular Cell(1)

Science Translational Medicine(1)

Área temáticas

Enfermedades(5)

Farmacología y terapéutica(3)

Fisiología humana(1)

Medicina y salud(1)

Área de conocimiento

Biotecnología(2)

Año de Publicación

Origen

Palabras Claves

Drug resistance(1)

A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer

Abstract: Targeted cancer therapies, although often effective, have limited utility owing to preexisting prima

Palabras claves:

Bader A.G., Chen X., Dysart S., Esteban A. Orellana, Kasinski A.L., Kelnar K., Shimer E., Slack F.J., Stahlhut C., Zhao J.

FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer

Abstract: MicroRNAs are small RNAs that negatively regulate gene expression posttranscriptionally. Because cha

Palabras claves:

Esteban A. Orellana, Kasinski A.L., Low P.S., Lyle L.T., Rangasamy L., Tenneti S.

METTL1-mediated m<sup>7</sup>G modification of Arg-TCT tRNA drives oncogenic transformation

Abstract: The emerging “epitranscriptomics” field is providing insights into the biological and pathological r

Palabras claves:

Arg-TCT, Cáncer, m G 7, METTL1, N -methylguanosine 7, oncogene, translation, tRNA

Ali R., Aspris D., Bernardes G.J.L., Bradley A., De Braekeleer E., Esteban A. Orellana, Fischer E.S., Garyfallos D.A., Gregory R.I., Gu M., Gutierrez A., Lim J., Liu Q., Mikutis S., Pirouz M., Sendinc E., Slack F.J., Tzelepis K., Vassiliou G.S., Yankova E., Zhang W.

Micrornas in cancer: A historical perspective on the path from discovery to therapy

Abstract: Recent progress in microRNA (miRNA) therapeutics has been strongly dependent on multiple seminal dis

Palabras claves:

Cáncer, History, microRNA, therapeutics

Esteban A. Orellana, Kasinski A.L.

Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias

Abstract: Resistance to asparaginase, an antileukemic enzyme that depletes asparagine, is a common clinical pr

Palabras claves:

acute leukemia, asparaginase, asparagine, Drug resistance, FBXW7, GSK3, proteasomal degradation, protein ubiquitination, synthetic lethality, Wnt signaling

Bauer D.E., Degar J., Esteban A. Orellana, Gregory R.I., Gutierrez A., Hinze L., Karim S., McGuckin C., Neuberg D.S., Pfirrmann M., Sacher J., Stanulla M., Stegmaier K., Stevenson K.E., Vinjamur D., Wagner F.F.