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An In-Silico Evaluation of Anthraquinones as Potential Inhibitors of DNA Gyrase B of Mycobacterium tuberculosis
ArticleAbstract: The World Health Organization reported that tuberculosis remains on the list of the top ten threatsPalabras claves:aminotriazole moiety, anthraquinones, DNA gyrase B, molecular dynamics, Mycobacterium tuberculosis, pharmacokinetic profileAutores:Andrea E. Cabrera Bermeo, Juan Carpio, Juan M. Carpio Arévalo, Juliana C. Amorim, Maritza R. Martínez León, Viviana E. Vásquez UrgilésFuentes:googlescopusVirtual screening, optimization and molecular dynamics analyses highlighting a pyrrolo[1,2-a]quinazoline derivative as a potential inhibitor of DNA gyrase B of Mycobacterium tuberculosis
ArticleAbstract: Tuberculosis is a disease that remains a significant threat to public health worldwide, and this isPalabras claves:Autores:Juan Carpio, Juliana C. AmorimFuentes:scopusPreparation and characterization of 4-nitrochalcone-folic acid-poly(methyl methacrylate) nanocapsules and cytotoxic activity on HeLa and NIH3T3 cells
ArticleAbstract: Chalcones of natural origin are plant metabolites which have been explored because of the cytotoxicPalabras claves:4-nitrochalcone, endocytosis, Folate receptor, Folic acid, Hela cells, Nanocapsules, Poly(methyl methacrylate)Autores:Cadena S.M.S.C., da Silva Córneo E., Feuser P.E., Hermes de Araújo P.H., Juan Carpio, Machado-de-Ávila R.A., Martinez G.R., Noleto G.R., Rocha M.E.M., Rossi G.R., Sayer C., Trindade E.S.Fuentes:scopus