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Comparison of the molecular coupling of the PLX4032 drug and the RNP CRISPR/CPF1 biopharmaceitical targeted to the metastatic melanoma type BRAF-V600E
OtherAbstract:Palabras claves:Autores:Alvarado Y.J., Bastidas M., González-Paz L.A., Lossada C.A., Luis S. Moncayo, Parra M.M., Pérez A.E., Sierra C.Fuentes:scopusBiological significance of the thermodynamic stability of crispr structures associated with unconventional functions
ArticleAbstract: The clustered regularly interspaced short palindromic repeats (CRISPR) are genetic sequences that coPalabras claves:CRISPR, MFE, transcriptionAutores:Alvarado Y.J., Fernández-Materán F.V., González-Paz L.A., Joan Vera-Villalobos, José Luis Paz, Lossada C.A., Luis S. Moncayo, Parra M.M., Pérez A.E., Portillo E., Romero F.Fuentes:scopusConformational change of ovalbumin induced by surface cavity binding of N-phthaloyl gamma-aminobutyric acid derivative: A study theoretical and experimental
ArticleAbstract: In this work is reported the study of the interaction between ovalbumin protein (OVA) and N-PhthaloyPalabras claves:Binding Studies, Molecular dynamic, Molecular Modeling Docking, Ovalbumin, Spectroscopic StudyAutores:Alvarado Y.J., González-Paz L.A., Joan Vera-Villalobos, José Luis Paz, Luis S. Moncayo, Mendez A., Restrepo J., Rodríguez-Lugo P., Romero F., Vera-Parra E.Fuentes:scopusDesign, specificity and thermodynamic stability of sgrnas directed to the e6 oncogene in hpv 16 and 18 for genetic therapy via crispr / cas
OtherAbstract:Palabras claves:Autores:Alvarado M.J., Alvarado Y.J., González-Paz L.A., Lossada C.A., Luis S. Moncayo, Parra M.M., Pérez A.E., Sierra C.Fuentes:scopus