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An in-silico analysis reveals 7,7′-bializarin as a promising DNA gyrase B inhibitor on Gram-positive and Gram-negative bacteria
ArticleAbstract: Bacterial diseases are considered by the World Health Organization to be one of the greatest threatsPalabras claves:7,7′-bializarin, anthraquinones, DNA gyrase B, ENTEROCOCCUS FAECALIS, ESCHERICHIA coli, Gram-negative, Gram-positive, Molecular dynamics simulation, Salmonella enterica subtype Typhi, Staphylococcus aureus, molecular dockingAutores:Juan Carpio, Juliana C. AmorimFuentes:scopusAn In-Silico Evaluation of Anthraquinones as Potential Inhibitors of DNA Gyrase B of Mycobacterium tuberculosis
ArticleAbstract: The World Health Organization reported that tuberculosis remains on the list of the top ten threatsPalabras claves:aminotriazole moiety, anthraquinones, DNA gyrase B, molecular dynamics, Mycobacterium tuberculosis, pharmacokinetic profileAutores:Andrea E. Cabrera Bermeo, Juan Carpio, Juan M. Carpio Arévalo, Juliana C. Amorim, Maritza R. Martínez León, Viviana E. Vásquez UrgilésFuentes:googlescopusGenome-Wide Proteomics and Phosphoproteomics Analysis of Trypanosoma cruzi During Differentiation
Book PartAbstract: Trypanosoma cruzi is a pathogenic protozoan that still has an impact on public health, despite the dPalabras claves:LC-MS/MS, Mass spectrometry, Metacyclogenesis, Phosphoproteomics, proteomics, TRYPANOSOMA CRUZIAutores:Batista M., de Paula Lima C.V., Juliana C. Amorim, Kugeratski F.G., Lucena A.C.R., Marchini F.K.Fuentes:scopusMacrophage activation and leishmanicidal activity by galactomannan and its oxovanadium (IV/V) complex in vitro
ArticleAbstract: Compounds that activate macrophage antimicrobial activity are potential targets for treatment of leiPalabras claves:Galactomannan, immunomodulators, leishmaniasis, Macrophages, Oxovanadium (IV/V) complexesAutores:Adriazola I.O., Amaral A.E.D., Correia B.L., Juliana C. Amorim, Mercê A.L.R., Noleto G.R., Petkowicz C.L.O.Fuentes:scopusModified pectin from Theobroma cacao induces potent pro-inflammatory activity in murine peritoneal macrophage
ArticleAbstract: In vitro effects of acetylated pectin (OP) isolated from cacao pod husks (Theobroma cacao L.), its pPalabras claves:chemical modification, Immunomodulator, macrophage, Pectin, Saponification, Theobroma cacao L.Autores:Juliana C. Amorim, Martinez G.R., Noleto G.R., Petkowicz C.L.O., Vriesmann L.C.Fuentes:scopusVirtual screening, optimization and molecular dynamics analyses highlighting a pyrrolo[1,2-a]quinazoline derivative as a potential inhibitor of DNA gyrase B of Mycobacterium tuberculosis
ArticleAbstract: Tuberculosis is a disease that remains a significant threat to public health worldwide, and this isPalabras claves:Autores:Juan Carpio, Juliana C. AmorimFuentes:scopusQuantitative phosphoproteome and proteome analyses emphasize the influence of phosphorylation events during the nutritional stress of Trypanosoma cruzi: the initial moments of in vitro metacyclogenesis
ArticleAbstract: Phosphorylation is an important event in cell signaling that is modulated by kinases and phosphatasePalabras claves:Metacyclogenesis, Nutritional stress, Phosphoproteomics, proteomics, Super-SILAC, TRYPANOSOMA CRUZIAutores:Batista M., de Godoy L.M.F., de Paula Lima C.V., Juliana C. Amorim, Krieger M.A., Lucena A.C.R., Marchini F.K.Fuentes:scopusQuantitative proteome and phosphoproteome analyses highlight the adherent population during Trypanosoma cruzi metacyclogenesis
ArticleAbstract: Trypanosoma cruzi metacyclogenesis is a natural process that occurs inside the triatomine vector andPalabras claves:Autores:Batista M., Da Cunha E.S., Juliana C. Amorim, Krieger M.A., Lima C.V.D.P., Lucena A.C.R., Marchini F.K., Sousa K.Fuentes:scopus