Mostrando 4 resultados de: 4
Interdisciplinarity in the rational design of enzyme inhibitory antimalarial drugs
ArticleAbstract: The rational development of pharmaceutical agents is a laborious and demanding research field. SuccePalabras claves:Antimalarials, enzyme inhibitors, Interdisciplinarity, MALARIAAutores:Ferrer M., Rosa E., Yonathan De J. ParraFuentes:scopus[(7-chloroquinolin-4-YL)amino]acetophenones and their copper(II) derivatives: Synthesis, characterization, computational studies and antimalarial activity
ArticleAbstract: The synthesis of the compounds [(7-chloroquinolin-4-yl)amino]acetophenones (4, 5) and their copper(IPalabras claves:Acetophenone, Antimalarial, Copper, DFT, fragmentation, quinolineAutores:Acosta M.E., Charris J.E., Colmenarez J.B., Félix Andueza, Ferrer M R.E., Gut J., Rosenthal P.J., Yonathan De J. ParraFuentes:scopusSynthesis, Leishmanicidal, Trypanocidal, Antiproliferative Assay and Apoptotic Induction of (2-Phenoxypyridin-3-yl)naphthalene-1(2H)-one Derivatives
ArticleAbstract: The coexistence of leishmaniasis, Chagas disease, and neoplasia in endemic areas has been extensivelPalabras claves:apoptosis, Cáncer, chalcone, leishmaniasis, TRYPANOSOMA CRUZIAutores:Ángel J.E., Blanco Z., Celis C., Charris J.E., de Sanctis J.B., Džubák P., Esteban Fernández-Moreira, García Y., Gurská S., Hajdůch M., Hegira Ramírez, Jhonny Correa-Abril, Martinez G.P., Mijares M.R., Mijoba A., Nahum Herrera, Serrano X., Yonathan De J. ParraFuentes:scopusSynthesis, characterization, crystal structure and antimalarial activity of (2E)-2-(1-{4-[(7-chloroquinolin-4-yl)amino]phenyl} ethylidene)hydrazine carbothioamide
ArticleAbstract: A simple synthesis and study by UV-vis, IR, NMR, ESI-CID-MS2 and X-ray diffraction of ((2E)-2-(1-{4-Palabras claves:Antimalarial activity, Crystal structure, ThiosemicarbazonesAutores:Bruno-Colmenarez J., Charris J.E., De Domínguez N.G., Ferrer R., Gut J., Lobo G.M., Rosenthal P.J., Yonathan De J. ParraFuentes:scopus