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Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats
ArticleAbstract: Purpose: Neuroinflammation may contribute to the pathogenesis of the cognitive symptoms of postoperaPalabras claves:aging, COGNITION, dopamine, Haloperidol, neuroinflammationAutores:Aoyama B., Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Nishigaki A., Shigematsu-Locatelli M., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusAcute postoperative pain exacerbates neuroinflammation and related delirium-like cognitive dysfunction in rats
ArticleAbstract: The acute neuroinflammatory response to surgery may play a key pathogenic role in postoperative deliPalabras claves:Delirium, neuroinflammation, postoperative painAutores:Aoyama B., Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Koyama T., Nishigaki A., Shigematsu-Locatelli M., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusEffects of epigallocatechin-3-gallate on systemic inflammation-induced cognitive dysfunction in aged rats
ArticleAbstract: Purpose: In this study, we examined the effects of epigallocatechin-3-gallate (EGCG), a green tea poPalabras claves:(−)-Epigallocatechin-3-gallate, Cognitive dysfunction, neuroinflammation, sepsisAutores:Aoyama B., Fabricio Miguel Locatelli, Kawano T., Nishigaki A., Shigematsu-Locatelli M., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusInvolvement of acute neuroinflammation in postoperative delirium-like cognitive deficits in rats
ArticleAbstract: Purpose: The purpose of this study was to investigate the age-, time-, and brain region-dependent poPalabras claves:Attention, Cognitive dysfunction, Fear memory, neuroinflammation, Postoperative deliriumAutores:Aoyama B., Fabricio Miguel Locatelli, Iwata H., Kawano T., Nishigaki A., Shigematsu-Locatelli M., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusResveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats
ArticleAbstract: The maladaptive response of aged microglia to surgery and consequent neuroinflammation plays a key pPalabras claves:Microglia, neuroinflammation, postoperative cognitive dysfunction, ResveratrolAutores:Aoyama B., Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Nishigaki A., Shigematsu-Locatelli M., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusPregabalin can prevent, but not treat, cognitive dysfunction following abdominal surgery in aged rats
ArticleAbstract: Aims The present study aimed to explore the preventive or therapeutic effect of peri-operative pregaPalabras claves:Microglia, neuroinflammation, Post-operative cognitive dysfunctionAutores:Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusPreventive effects of dexmedetomidine on the development of cognitive dysfunction following systemic inflammation in aged rats
ArticleAbstract: Purpose: In the present study, we examined whether and by what mechanisms dexmedetomidine (DMED) prePalabras claves:Cognitive function, Dexmedetomidine, Microglia, neuroinflammationAutores:Aoyama B., Fabricio Miguel Locatelli, Kawano T., Nishigaki A., Shigematsu-Locatelli M., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopusThe role of hippocampal insulin signaling on postoperative cognitive dysfunction in an aged rat model of abdominal surgery
ArticleAbstract: Aims This study aimed to investigate the role of central insulin signaling, including glycogen synthPalabras claves:Insulin, Microglia, neuroinflammation, Postoperative cognitive disordersAutores:Aoyama B., Eguchi S., Fabricio Miguel Locatelli, Iwata H., Kawano T., Nishigaki A., Tateiwa H., Yamanaka D., Yokoyama M.Fuentes:scopus