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scopus(7)
CD69 is a direct HIF-1α target gene in hypoxia as a mechanism enhancing expression on tumor-infiltrating T lymphocytes
ArticleAbstract: CD69 is an early activation marker on the surface of T lymphocytes undergoing activation by cognatePalabras claves:CD69, HIF-1α, Hypoxia, tumor microenvironment, tumor-infiltrating lymphocytes (TILs)Autores:Aragonés J., Aznar M.Á., Azpilikueta A., Bolaños E., de la Fuente H., Etxeberria I., Garasa S., Labiano S., Maiso P., Manuel Ortiz de Landázuri, Meléndez-Rodríguez F., Melero I., Molina C., Palazón A., Sánchez-Paulete A.R., Sánchez‐Madrid F., Teijeira A.Fuentes:scopusMutant versions of von Hippel-Lindau (VHL) can protect HIF1α from SART1-mediated degradation in clear-cell renal cell carcinoma
ArticleAbstract: Inactivation of the von Hippel-Lindau (VHL) tumor suppressor drives the development of clear-cell rePalabras claves:Autores:Acosta-Iborra B., Aragonés J., Balsa E., Elorza A., Fuertes-Yebra E., Manuel Ortiz de Landázuri, Ordóñez-NavadijoFuentes:scopusInadequate activation of the GTPase RhoA contributes to the lack of fibronectin matrix assembly in von Hippel-Lindau protein-defective renal cancer cells
ArticleAbstract: The von Hippel-Lindau (VHL) tumor suppressor gene regulates extracellular matrix deposition. In VHLPalabras claves:Autores:Calzada M.J., Castellanos M.C., Del Cerro M.H., Esteban M.A., Feijóo-Cuaresma M., García‐Pardo A., Manuel Ortiz de Landázuri, Maqueda A., Méndez F., Naranjo-Suárez S., Vazquez S.N.Fuentes:scopusVon Hippel-Lindau tumor suppressor protein regulates the assembly of intercellular junctions in renal cancer cells through hypoxia-inducible factor-independent mechanisms
ArticleAbstract: Inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene is responsible for the developmentPalabras claves:Autores:Calzada M.J., Castellanos M.C., Esteban M.A., Feijóo-Cuaresma M., Manuel Ortiz de Landázuri, Méndez F., Naranjo-Suárez S., Ohh M., Temes E., Yáñez-Mó M.Fuentes:scopusRole of the von Hippel-Lindau tumor suppressor gene in the formation of β1-integrin fibrillar adhesions
ArticleAbstract: The von Hippel-Lindau tumor suppressor gene (VHL) is absent or inactivated in the VHL cancer syndromPalabras claves:Autores:Álvarez-Tejado M., Ávila P., Esteban-Barragán M.A., García‐Pardo A., Gutiérrez M.D., Manuel Ortiz de Landázuri, Sánchez‐Madrid F.Fuentes:scopusSpecific Oncolytic Effect of a New Hypoxia-Inducible Factor-Dependent Replicative Adenovirus on von Hippel-Lindau-Defective Renal Cell Carcinomas
ArticleAbstract: Mutations in the von Hippel-Lindau (VHL) tumor suppressor gene are responsible for a hebkp_reditaryPalabras claves:Autores:Aragonés J., Castellanos M.C., Cuevas Y., Esteban M.A., Hernández-Alcoceba R., Manuel Ortiz de Landázuri, Martin-Puig S., Naranjo-Suárez S., Peso L.D.Fuentes:scopusTargeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: The METOXIA consortium
ReviewAbstract: The hypoxic areas of solid cancers represent a negative prognostic factor irrespective of which treaPalabras claves:Bioreductive compounds, cancer-treatment resistance, carbonic anhydrase inhibitors, dual-activity compounds, non-invasive oxygen detection, targets for new treatmentAutores:Ahmed A., Alsner J., Ashcroft M., Buffa F.M., Busk M., Calzada M.J., Cao Y., Chiche J., Cojocari D., Dubois L., Ebbesen P., Flamm H., Flatmark K., Gieling R.G., Görlach A., Haider S., Harris A.L., Jobst G., Kieninger J., Koritzinsky M., Kunkler I.H., Lambin P., Langdon S.P., Lyng H., Manuel Ortiz de Landázuri, Marchiq I., Mazure N., Meehan J., Moser I., Mujcic H., Overgaard J., Parks S., Pastorekova S., Peso L.D., Pettersen E.O., Pouyssegur J., Ree A.H., Rouschop K.M., Scozzafava A., Singleton D.C., Supuran C.T., Toustrup K., Urban G., Ward C., Weltin A., Williams K.J., Wouters B.G.Fuentes:scopus