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Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase
ArticleAbstract: Hypoxia-inducible factors (HIF) are heterodimeric (α/β) transcription factors that play a fundamentaPalabras claves:Autores:Acosta-Iborra B., Aragonés J., Castellanos M.C., Feijóo-Cuaresma M., Manuel Ortiz de Landázuri, Martin-Puig S., Olmos G., Temes E.Fuentes:scopusActivators of protein kinase C up-regulate the cell surface expression of CD2 and CD5 T cell glycoproteins
ArticleAbstract: Activation of human T cells through the CD3-T cell receptor complex caused an augmentation in the cePalabras claves:Autores:Alonso M., Cardenas L., Carrera A.C., Manuel Ortiz de Landázuri, Sánchez‐Madrid F., Tugores A.Fuentes:scopusEvidence for the Involvement of Diacylglycerol Kinase in the Activation of Hypoxia-inducible Transcription Factor 1 by Low Oxygen Tension
ArticleAbstract: Hypoxia-inducible factor 1 (HIF-1) induces a gene expression program essential for the cellular adapPalabras claves:Autores:Alfranca A., Aragonés J., Jones D.R., Manuel Ortiz de Landázuri, Martin-Puig S., Mérida I., San Juan M.A., Vara A., Vidal F.Fuentes:scopusDithiocarbamates trigger differentiation and induction of CD11c gene through AP-1 in the myeloid lineage
ArticleAbstract: It has recently been shown that the alteration of the cell-redox status affects the transcription faPalabras claves:Autores:Aragonés J., Corbí A.L., Del Arco P.G., López-Cabrera M., López-Rodríguez C., Manuel Ortiz de Landázuri, Redondo J.M.Fuentes:scopusDown-regulation of hypoxia-inducible factor-2 in PC12 cells by nerve growth factor stimulation
ArticleAbstract: Cellular responses to low oxygen tension are mediated, at least in part, by the activation of the hyPalabras claves:Autores:Álvarez-Tejado M., Castellanos M.C., Manuel Ortiz de Landázuri, Naranjo-Suárez S., Peso L.D., Vara A.Fuentes:scopusLack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension
ArticleAbstract: Hypoxia-inducible factors (HIF) belong to an evolutionary conserved family of transcription factors,Palabras claves:Autores:Alfranca A., Álvarez-Tejado M., Aragonés J., Manuel Ortiz de Landázuri, Peso L.D., Vara A.Fuentes:scopusHypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells. Protective role in apoptosis
ArticleAbstract: Hypoxia is a common environmental stress that influences signaling pathways and cell function. SeverPalabras claves:Autores:Álvarez-Tejado M., Carrera A.C., Jiménez C., Manuel Ortiz de Landázuri, Naranjo-Suárez S., Peso L.D.Fuentes:scopusInadequate activation of the GTPase RhoA contributes to the lack of fibronectin matrix assembly in von Hippel-Lindau protein-defective renal cancer cells
ArticleAbstract: The von Hippel-Lindau (VHL) tumor suppressor gene regulates extracellular matrix deposition. In VHLPalabras claves:Autores:Calzada M.J., Castellanos M.C., Del Cerro M.H., Esteban M.A., Feijóo-Cuaresma M., García‐Pardo A., Manuel Ortiz de Landázuri, Maqueda A., Méndez F., Naranjo-Suárez S., Vazquez S.N.Fuentes:scopusRole of Iron (II)-2-Oxoglutarate-dependent Dioxygenases in the Generation of Hypoxia-induced Phosphatidic Acid through HIF-1/2 and von Hippel-Lindau-independent Mechanisms
ArticleAbstract: Hypoxia-inducible factors (HIF-1/HIF-2) govern the expression of critical genes for cellular adaptatPalabras claves:Autores:Aragonés J., Jones D.R., Manuel Ortiz de Landázuri, Martin-Puig S., Olmos G., Temes E.Fuentes:scopusThe von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen
ArticleAbstract: Most of the genes induced by hypoxia are regulated by a family of transcription factors termed hypoxPalabras claves:Autores:Castellanos M.C., Cuevas Y., Manuel Ortiz de Landázuri, Martin-Puig S., Olmos G., Peso L.D., Temes E.Fuentes:scopus