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CNS and Neurological Disorders - Drug Targets(5)
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25 years of research on global asphyxia in the immature rat brain
ReviewAbstract: Hypoxic-ischemic encephalopathy remains a common cause of brain damage in neonates. Preterm infantsPalabras claves:Encephalopathy, functional outcome, Hypoxic-ischemia, Preterm infant, SubmersionAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Kramer B.W., Steinbusch H.W.M., van den Hove D.L.A., Vles J.S.H.Fuentes:scopusA combined behavioral and morphological study on the effects of fetal asphyxia on the nigrostriatal dopaminergic system in adult rats
ArticleAbstract: Fetal asphyxic insults in the brain are known to be associated with developmental neurological problPalabras claves:dopamine, Fetal asphyxia, Glial fibrillary acidic protein (GFAP), locomotion, Open field, RAT, Striatum, Substantia nigra, Tyrosine hydroxylase (TH), VentriculomegalyAutores:Antonio Wenceslao Danilo Gavilanes, Blanco C.E., Steinbusch H., Steinbusch H.W.M., Strackx E., van den Hove D.L.A., Vles J.S.H.Fuentes:scopusA new hope: Mitochondria, a critical factor in the war against prions
ArticleAbstract: Prion diseases encompass a group of incurable neurodegenerative disorders that occur due to the misfPalabras claves:Extracellular mitochondria, Mitochondrial therapy, MtDNA, Neurodegenerative Disease, PrionsAutores:Andrés Caicedo, Antonio Wenceslao Danilo Gavilanes, DIEGO GUILLERMO BARBA MAGGI, Eduardo Arízaga, Karina Castillo, Kevin Zambrano, Paola RobayoFuentes:scopusA simple quantitative method analysing amikacin, gentamicin, and vancomycin levels in human newborn plasma using ion-pair liquid chromatography/tandem mass spectrometry and its applicability to a clinical study
ArticleAbstract: Neuroprotective controlled therapeutic hypothermia is the standard of care for newborns suffering pePalabras claves:Amikacin, Gentamicin, hypothermia, LC-MS/MS, neonates, VancomycinAutores:Antonio Wenceslao Danilo Gavilanes, Bijleveld Y., Cools F., De Haan T.R., de Jonge R., Dijk P., Dijkman K.P., Groenendaal F., Jorjani S., Mathôt R., Nuytemans D., Rijken M., Toersche J., van der Lee J., van Heijst A., Van Straaten H.L.M., Zonnenberg I.A.Fuentes:scopusChorioamnionitis induced by intraamniotic lipopolysaccharide resulted in an interval-dependent increase in central nervous system injury in the fetal sheep
ArticleAbstract: Objective: We quantified the impact of chorioamnionitis on both the white and gray matter structuresPalabras claves:Central nervous system, chorioamnionitis, fetal inflammation, LIPOPOLYSACCHARIDE, OligodendrocytesAutores:Antonio Wenceslao Danilo Gavilanes, Cornips E., Gantert M., Garnier Y., Kramer B.W., Steinbusch H., Steinbusch H.W.M., Strackx E., van den Hove D.L.A., Vles J.S.H., Zimmermann L.J.I.Fuentes:scopusChorioamnionitis: A multiorgan disease of the fetus
Conference ObjectAbstract: The bacterial infection of chorion and amnion is a common finding in premature delivery and is referPalabras claves:adverse outcome, antenatal inflammation, Development, organ injury, repairAutores:Antonio Wenceslao Danilo Gavilanes, Been J.V., Gantert M., Garnier Y., Kramer B.W., Zimmermann L.J.I.Fuentes:scopusCirculating S100B and Adiponectin in Children Who Underwent Open Heart Surgery and Cardiopulmonary Bypass
ArticleAbstract: Background. S100B protein, previously proposed as a consolidated marker of brain damage in congenitaPalabras claves:Autores:Anastasia L., Antonio Wenceslao Danilo Gavilanes, Conforti E., Frigiola A., Gazzolo D., Giamberti A., Livolti G., Satriano A., Tettamanti G., Varrica A., Vles H.J.S., Zimmermann L.J.I.Fuentes:scopusClinical Implications of Epigenetic Dysregulation in Perinatal Hypoxic-Ischemic Brain Damage
ReviewAbstract: Placental and fetal hypoxia caused by perinatal hypoxic-ischemic events are major causes of stillbirPalabras claves:Biomarker, DNA methylation, histone modifications, Hypoxia, hypoxic-ischemic encephalopathy, ischemia, microRNAsAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Bruno M.A., Bustelo M., Loidl C.F., Steinbusch H.W.M., van den Hove D.L.A.Fuentes:scopusComparison of three non-invasive ventilation strategies (NSIPPV/BiPAP/NCPAP) for RDS in VLBW infants
ArticleAbstract: Background: Non-invasive ventilation (NIV) significantly changed the management of respiratory distrPalabras claves:BiLevel-CPAP, nasal synchronized intermittent positive pressure ventilation (NSIPPV), nCPAP, NIV, RDSAutores:Antonio Wenceslao Danilo Gavilanes, Colivicchi M., Ferraù V., Gazzolo D., Gitto E., Lista G., Lupo E., Ricotti A., Salvo V., Zimmermann L.J.I.Fuentes:scopusAvailability and Quality of Grief and Bereavement Care in Pediatric Intensive Care Units Around the World, Opportunities for Improvement
ArticleAbstract: Pediatric Intensive Care Units (PICUs) provide multidisciplinary care to critically ill children andPalabras claves:bereavement, end of life, grief, Pediatric critical care, pediatric palliative careAutores:Andrea P. Icaza-Freire, Antonio Wenceslao Danilo Gavilanes, Aronowitz D., Barrera R., Gabriela Bustamante, Kevin Zambrano, Michelle Grunauer, Mikesell C.Fuentes:scopus