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A correlation between geometric features and analgesic activity for a series of cannabinoid compounds
ArticleAbstract:Palabras claves:Analgesic activity, Cannabinoids, Geometric featuresAutores:Arroio A., Da Silva A.B.F., Saulo L. Silva, Trsic M.Fuentes:scopusA multivariate study on flavonoid compounds scavenging the peroxynitrite free radical
ArticleAbstract: The goal of this study is to select electronic properties (variables or descriptors) responsible forPalabras claves:flavonoids, Free radicals, HCA, Knn, pattern recognition, PCa, PeroxinitriteAutores:Calgarotto A.K., Comar M., Da Silva A.B.F., Honório K.M., Marangoni S., Miotto S., Oliveira K.M.T., Saulo L. Silva, Silva J.L.Fuentes:scopusA novel phospholipase A<inf>2</inf> (D49) from the venom of the Crotalus oreganus abyssus (North American Grand Canyon rattlesnake)
ArticleAbstract: Currently, Crotalus viridis was divided into two species: Crotalus viridis and Crotalus oreganus. ThPalabras claves:Autores:Acosta G.A., Alberício F., Baldasso P.A., Caballol M.A.O., Carvalho B.M.A., de Azevedo Calderon L., Honório K.M., Maltarollo V.G., Marangoni S., Martins W., Oliveira E., Ribeiro R.I.M.A., Saulo L. Silva, Soares A.M., Stábeli R.G.Fuentes:scopusA novel synthetic peptide inspired on Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
ArticleAbstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics aPalabras claves:Antibacterial activity, Biomimetic peptide, Phospholipase A 2, Snake venomAutores:Bruno Mendes, Fernandes P.A., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Marangoni S., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopusCoaTx-II, a new dimeric Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles
ArticleAbstract: Snake venoms are rich and intriguing sources of biologically-active molecules that act on target celPalabras claves:Antibacterial effect, Crotalus oreganus abyssus, Lys49 phospholipase A 2, Myotoxicity, Snake venomAutores:de Azevedo Calderon L., González W., José Rafael de Almeida, Lancellotti M., Marangoni S., Ramírez D., Saulo L. Silva, Soares A.M.Fuentes:googlescopusBbMP-1, a new metalloproteinase isolated from Bothrops brazili snake venom with in vitro antiplasmodial properties
ArticleAbstract: This study describes the biochemical and functional characterization of a new metalloproteinase namePalabras claves:Antiplasmodial activity, B. brazili, Enzymatic characterization, Functional characterization, Metalloproteinase, Snake venomAutores:Aguiar A.C.C., Alberício F., de Azevedo Calderon L., Fernandes C.F.C., Honório K.M., Kayano A.M., Krettli A.U., Maltarollo V.G., Medeiros P.S.M., Oliveira E., Saulo L. Silva, Simões-Silva R., Soares A.M., Stábeli R.G., Zuliani J.P.Fuentes:scopusBbrzSP-32, the first serine protease isolated from Bothrops brazili venom: Purification and characterization
ArticleAbstract: Snake venom toxins are related not only in detention, death and the promotion of initial digestion oPalabras claves:Biotechnology, Enzyme, Snake venom, Thrombin-like, VIPERIDAEAutores:Acosta G.A., Alberício F., de Azevedo Calderon L., Domingos T.F.S., Fuly A.L., Kayano A.M., Moura L.A., Oliveira E., Saulo L. Silva, Soares A.M., Stábeli R.G., Zanchi F.B., Zaqueo K.D., Zuliani J.P.Fuentes:scopusBiochemical and functional characterization of parawixia bistriata spider venom with potential proteolytic and larvicidal activities
ArticleAbstract: Toxins purified from the venom of spiders have high potential to be studied pharmacologically and biPalabras claves:Autores:Coutinho-Neto A., De Almeida E Silva A., de Azevedo Calderon L., Fernandes C.F.C., Gimenez G.S., Kayano A.M., Marcussi S., Saulo L. Silva, Simões-Silva R., Soares A.M., Stábeli R.G., Trindade F., Zuliani J.P.Fuentes:scopusBiochemical and functional studies of ColTx-I, a new myotoxic phospholipase A<inf>2</inf> isolated from Crotalus oreganus lutosus (Great Basin rattlesnake) snake venom
ArticleAbstract: Commonly, phospholipases A2 (PLA2s) play key roles in the pathogenesis of the local tissue damage chPalabras claves:Biological activities, Crotalus oreganus lutosus, Myotoxin, Phospholipase A 2, Snake venomAutores:de Azevedo Calderon L., José Rafael de Almeida, Marangoni S., Resende L.M., Ribeiro R.I.M.A., Saulo L. Silva, Silva A.G., Soares A.M., Stábeli R.G.Fuentes:scopusBiological and biochemical characterization of new basic phospholipase A<inf>2</inf> BmTX-I isolated from Bothrops moojeni snake venom
ArticleAbstract: BmTX-I, an Asp49 phospholipase A2, was purified from Bothrops moojeni venom after only one chromatogPalabras claves:Asp49 phospholipase A2, characterization, Edema-forming activity, Myonecrosis and interleukin-6 response, Neuromuscular blockade, Snake venomAutores:Baldasso P.A., Calgarotto A.K., Damico D.C.S., Eberlin M.N., Marangoni S., Ponce-Soto L.A., Saulo L. Silva, Souza G.H.M.F.Fuentes:scopus