Mostrando 10 resultados de: 25
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Enzymatic and structural characterization of a basic phospholipase A <inf>2</inf> from the sea anemone Condylactis gigantea
ArticleAbstract: This work aimed at the isolation and structural/functional characterization of a phospholipase A 2 (Palabras claves:Condylactis gigantea, Functional characterization, molecular modeling, Phospholipase A 2, Phylogenetic analysis, Primary structure, Sea anemonesAutores:Fuly A.L., González J., Marchi-Salvador D.P., Marcussi S., Monte A.d., Romero L., Saulo L. Silva, Silva F.P., Soares A.M., Stábeli R.G.Fuentes:scopusExploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A<inf>2,</inf> AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom
ArticleAbstract: Phospholipases A2 (PLA2s) constitute a class of extensively studied toxins, isolated from snake venoPalabras claves:Acidic phospholipase A 2, Agkistrodon piscivorus leucostoma, Pharmacological activity, Snake venomAutores:Collaço R.C.O., de Azevedo Calderon L., González W., Jose Rafael de Almeida, Marangoni S., Ramírez D., Resende L.M., Saulo L. Silva, Schezaro-Ramos R., Simioni L.R., Soares A.M.Fuentes:orcidscopusGenotoxic effect of Bothrops snake venoms and isolated toxins on human lymphocyte DNA
ArticleAbstract: In the present study, micronucleus with cytokinesis blocking and comet assays were used to evaluatePalabras claves:Bothrops snake, Comet, Genotoxic potential, Micronucleus, Snake venom toxinsAutores:de Azevedo Calderon L., Greggi Antunes L.M., Marcussi S., Menaldo D.L., Santos-Filho N.A., Saulo L. Silva, Silva Pereira L.L., Soares A.M., Stábeli R.G., Zuliani J.P.Fuentes:scopusCytotoxic evaluation of essential oil from Casearia sylvestris Sw on human cancer cells and erythrocytes
ArticleAbstract: Casearia sylvestris (Flacourtiaceae) is a plant popularly known as "guaçatonga" and it is used by inPalabras claves:Casearia sylvestris, Cytotoxicity, Erythrocytes, Essential oil, MTT, sesquiterpenesAutores:Chaar J.S., Figueiredo P.M.S., Saulo L. Silva, Yano T.Fuentes:scopusA novel synthetic peptide inspired on Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
ArticleAbstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics aPalabras claves:Antibacterial activity, Biomimetic peptide, Phospholipase A 2, Snake venomAutores:Bruno Mendes, Fernandes P.A., Gomes P.A.D.C., Jose Rafael de Almeida, Lancellotti M., Marangoni S., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:orcidscopusCoaTx-II, a new dimeric Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles
ArticleAbstract: Snake venoms are rich and intriguing sources of biologically-active molecules that act on target celPalabras claves:Antibacterial effect, Crotalus oreganus abyssus, Lys49 phospholipase A 2, Myotoxicity, Snake venomAutores:de Azevedo Calderon L., González W., Jose Rafael de Almeida, Lancellotti M., Marangoni S., Ramírez D., Saulo L. Silva, Soares A.M.Fuentes:googleorcidscopusAntimicrobial activity of bergenin from Endopleura uchi (Huber) Cuatrec
ArticleAbstract: Endopleura uchi (Huber) Cuatrec. is an Amazon species traditionally used as treatment for inflammatiPalabras claves:antibacterial, Antifungal, Candida, Humiriaceae, Uxi-amareloAutores:de Oliveira V.G., Nunomura R.d.C.S., Saulo L. Silva, Yano T.Fuentes:scopusBbMP-1, a new metalloproteinase isolated from Bothrops brazili snake venom with in vitro antiplasmodial properties
ArticleAbstract: This study describes the biochemical and functional characterization of a new metalloproteinase namePalabras claves:Antiplasmodial activity, B. brazili, Enzymatic characterization, Functional characterization, Metalloproteinase, Snake venomAutores:Aguiar A.C.C., Alberício F., de Azevedo Calderon L., Fernandes C.F.C., Honório K.M., Kayano A.M., Krettli A.U., Maltarollo V.G., Medeiros P.S.M., Oliveira E., Saulo L. Silva, Simões-Silva R., Soares A.M., Stábeli R.G., Zuliani J.P.Fuentes:scopusBbrzSP-32, the first serine protease isolated from Bothrops brazili venom: Purification and characterization
ArticleAbstract: Snake venom toxins are related not only in detention, death and the promotion of initial digestion oPalabras claves:Biotechnology, Enzyme, Snake venom, Thrombin-like, VIPERIDAEAutores:Acosta G.A., Alberício F., de Azevedo Calderon L., Domingos T.F.S., Fuly A.L., Kayano A.M., Moura L.A., Oliveira E., Saulo L. Silva, Soares A.M., Stábeli R.G., Zanchi F.B., Zaqueo K.D., Zuliani J.P.Fuentes:scopusBiochemical and functional studies of ColTx-I, a new myotoxic phospholipase A<inf>2</inf> isolated from Crotalus oreganus lutosus (Great Basin rattlesnake) snake venom
ArticleAbstract: Commonly, phospholipases A2 (PLA2s) play key roles in the pathogenesis of the local tissue damage chPalabras claves:Biological activities, Crotalus oreganus lutosus, Myotoxin, Phospholipase A 2, Snake venomAutores:de Azevedo Calderon L., Jose Rafael de Almeida, Marangoni S., Resende L.M., Ribeiro R.I.M.A., Saulo L. Silva, Silva A.G., Soares A.M., Stábeli R.G.Fuentes:orcidscopus