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Toxicon(3)
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Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology(1)
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Farmacología y terapéutica(9)
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Anti-platelet aggregation activity of two novel acidic Asp49-phospholipases A<inf>2</inf> from Bothrops brazili snake venom
ArticleAbstract: Phospholipases A2 (PLA2s) are important enzymes present in snake venoms and are related to a wide spPalabras claves:Acidic phospholipases A 2, Anti-platelet aggregation activity, Bothrops brazili, Snake venomAutores:Alfonso J.J., Fuly A.L., Gómez A.F., Gomez M.C.V., José Rafael de Almeida, Kayano A.M., Moura L.A., Oliveira E., Saulo L. Silva, Simões-Silva R., Soares A.M., Sobrinho J.C., Souza V.R., Zanchi F.B., Zuliani J.P.Fuentes:googlescopusCorrigendum to “Exploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A2, AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom” [Toxicon 127 (2017) 22–36] (S004101011730003X) (10.1016/j.toxicon.2017.01.002)
OtherAbstract: 2.5.2. Homology modeling and molecular dynamic studies The homology model of AplTx-I were built (usiPalabras claves:Autores:Collaço R.C.O., de Azevedo Calderon L., González W., José Rafael de Almeida, Marangoni S., Ramírez D., Ramos R.S., Resende L.M., Saulo L. Silva, Simioni L.R., Soares A.M.Fuentes:scopusCytotoxic evaluation of essential oil from Casearia sylvestris Sw on human cancer cells and erythrocytes
ArticleAbstract: Casearia sylvestris (Flacourtiaceae) is a plant popularly known as "guaçatonga" and it is used by inPalabras claves:Casearia sylvestris, Cytotoxicity, Erythrocytes, Essential oil, MTT, sesquiterpenesAutores:Chaar J.S., Figueiredo P.M.S., Saulo L. Silva, Yano T.Fuentes:scopusGenotoxic effect of Bothrops snake venoms and isolated toxins on human lymphocyte DNA
ArticleAbstract: In the present study, micronucleus with cytokinesis blocking and comet assays were used to evaluatePalabras claves:Bothrops snake, Comet, Genotoxic potential, Micronucleus, Snake venom toxinsAutores:de Azevedo Calderon L., Greggi Antunes L.M., Marcussi S., Menaldo D.L., Santos-Filho N.A., Saulo L. Silva, Silva Pereira L.L., Soares A.M., Stábeli R.G., Zuliani J.P.Fuentes:scopusEvaluation of the genotoxicity of Crotalus durissus terrificus snake venom and its isolated toxins on human lymphocytes
ArticleAbstract: In the present study, experiments were carried out to evaluate the mutagenic potential and genotoxicPalabras claves:Comet, Crotalus durissus terrificus, genotoxicity, Micronucleus, Snake venom toxinsAutores:Greggi Antunes L.M., Marcussi S., Mazzi M.V., Menaldo D.L., Santos P.R.S., Santos-Filho N.A., Saulo L. Silva, Silveira L.B., Soares A.M., Stábeli R.G.Fuentes:scopusInhibition of gelatinase activity of mmp-2 and mmp-9 by extracts of Bauhinia ungulata L.
ArticleAbstract: Metastasis is responsible for the majority of cancer-related deaths. Tumour invasion and metastasisPalabras claves:Medicinal Plant, Metalloproteinase, Pata de vaca, Phytochemical Study, ZymogramAutores:de Faria Gomes I.N., de Fátima Nunes D.A., dos Santos K.M., Ribeiro R.I.M.A., Saulo L. SilvaFuentes:scopusIsolation, structural and functional characterization of a new Lys49 phospholipase A<inf>2</inf> homologue from Bothrops neuwiedi urutu with bactericidal potential
ArticleAbstract: Snake venom is a complex mixture of active compounds consisting of 80-90% proteins and peptides thatPalabras claves:bactericidal activity, Bothrops neuwiedi, Phospholipase A 2, Snake venomAutores:Corrêa E.A., de Azevedo Calderon L., Diniz-Sousa R., José Rafael de Almeida, Kayano A.M., Marangoni S., Matos N.B., Resende L.M., Saulo L. Silva, Setúbal S.S., Soares A.M., Zanchi F.B., Zuliani J.P.Fuentes:googlescopusThe chemistry of snake venom and its medicinal potential
ReviewAbstract: The fascination and fear of snakes dates back to time immemorial, with the first scientific treatisePalabras claves:Autores:Fernandes P.A., Oliveira A.L., Ramos M.J., Saulo L. Silva, Soares A.M., Viegas M.F.Fuentes:scopusLessons from a Single Amino Acid Substitution: Anticancer and Antibacterial Properties of Two Phospholipase A<inf>2</inf>-Derived Peptides
ArticleAbstract: The membrane-active nature of phospholipase A2-derived peptides makes them potential candidates forPalabras claves:Agkistrodon, leucine, Membrane, Phenylalanine, Venom peptidesAutores:Alves C., Bruno Mendes, Fernandes P.A., Franchi G.C., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopusPotential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents
ArticleAbstract: Phospholipase A2 toxins present in snake venoms interact with biological membranes and serve as struPalabras claves:Leishmanicidal activity, Oligoarginine, peptide, PhospholipaseAutores:Bruno Mendes, Gadelha F.R., Gomes P.A.D.C., José Rafael de Almeida, Miguel D.C., Saulo L. Silva, Vale N.Fuentes:scopus