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CoaTx-II, a new dimeric Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles
ArticleAbstract: Snake venoms are rich and intriguing sources of biologically-active molecules that act on target celPalabras claves:Antibacterial effect, Crotalus oreganus abyssus, Lys49 phospholipase A 2, Myotoxicity, Snake venomAutores:de Azevedo Calderon L., González W., José Rafael de Almeida, Lancellotti M., Marangoni S., Ramírez D., Saulo L. Silva, Soares A.M.Fuentes:googlescopusAssessing the stability of historical and desiccated snake venoms from a medically important Ecuadorian collection
ArticleAbstract: Bothrops asper and Bothrops atrox are important venomous snakes from Ecuador responsible for the mosPalabras claves:Desiccated venom, Proteomic, Snake venom, stability, ToxicologicalAutores:Bruno Mendes, Caldeira C.A.S., Fausto Zaruma-Torres, José Rafael de Almeida, Laines J., Noroska Gabriela Salazar Mogollón, Pico J., Ricardo S.P. Patiño, Saulo L. Silva, Terán M.Fuentes:googlescopusBbMP-1, a new metalloproteinase isolated from Bothrops brazili snake venom with in vitro antiplasmodial properties
ArticleAbstract: This study describes the biochemical and functional characterization of a new metalloproteinase namePalabras claves:Antiplasmodial activity, B. brazili, Enzymatic characterization, Functional characterization, Metalloproteinase, Snake venomAutores:Aguiar A.C.C., Alberício F., de Azevedo Calderon L., Fernandes C.F.C., Honório K.M., Kayano A.M., Krettli A.U., Maltarollo V.G., Medeiros P.S.M., Oliveira E., Saulo L. Silva, Simões-Silva R., Soares A.M., Stábeli R.G., Zuliani J.P.Fuentes:scopusBbrzSP-32, the first serine protease isolated from Bothrops brazili venom: Purification and characterization
ArticleAbstract: Snake venom toxins are related not only in detention, death and the promotion of initial digestion oPalabras claves:Biotechnology, Enzyme, Snake venom, Thrombin-like, VIPERIDAEAutores:Acosta G.A., Alberício F., de Azevedo Calderon L., Domingos T.F.S., Fuly A.L., Kayano A.M., Moura L.A., Oliveira E., Saulo L. Silva, Soares A.M., Stábeli R.G., Zanchi F.B., Zaqueo K.D., Zuliani J.P.Fuentes:scopusBiochemical and functional studies of ColTx-I, a new myotoxic phospholipase A<inf>2</inf> isolated from Crotalus oreganus lutosus (Great Basin rattlesnake) snake venom
ArticleAbstract: Commonly, phospholipases A2 (PLA2s) play key roles in the pathogenesis of the local tissue damage chPalabras claves:Biological activities, Crotalus oreganus lutosus, Myotoxin, Phospholipase A 2, Snake venomAutores:de Azevedo Calderon L., José Rafael de Almeida, Marangoni S., Resende L.M., Ribeiro R.I.M.A., Saulo L. Silva, Silva A.G., Soares A.M., Stábeli R.G.Fuentes:scopusBiological and biochemical characterization of new basic phospholipase A<inf>2</inf> BmTX-I isolated from Bothrops moojeni snake venom
ArticleAbstract: BmTX-I, an Asp49 phospholipase A2, was purified from Bothrops moojeni venom after only one chromatogPalabras claves:Asp49 phospholipase A2, characterization, Edema-forming activity, Myonecrosis and interleukin-6 response, Neuromuscular blockade, Snake venomAutores:Baldasso P.A., Calgarotto A.K., Damico D.C.S., Eberlin M.N., Marangoni S., Ponce-Soto L.A., Saulo L. Silva, Souza G.H.M.F.Fuentes:scopusAnti-platelet aggregation activity of two novel acidic Asp49-phospholipases A<inf>2</inf> from Bothrops brazili snake venom
ArticleAbstract: Phospholipases A2 (PLA2s) are important enzymes present in snake venoms and are related to a wide spPalabras claves:Acidic phospholipases A 2, Anti-platelet aggregation activity, Bothrops brazili, Snake venomAutores:Alfonso J.J., Fuly A.L., Gómez A.F., Gomez M.C.V., José Rafael de Almeida, Kayano A.M., Moura L.A., Oliveira E., Saulo L. Silva, Simões-Silva R., Soares A.M., Sobrinho J.C., Souza V.R., Zanchi F.B., Zuliani J.P.Fuentes:googlescopusA novel synthetic peptide inspired on Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
ArticleAbstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics aPalabras claves:Antibacterial activity, Biomimetic peptide, Phospholipase A 2, Snake venomAutores:Bruno Mendes, Fernandes P.A., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Marangoni S., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopusExploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A<inf>2,</inf> AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom
ArticleAbstract: Phospholipases A2 (PLA2s) constitute a class of extensively studied toxins, isolated from snake venoPalabras claves:Acidic phospholipase A 2, Agkistrodon piscivorus leucostoma, Pharmacological activity, Snake venomAutores:Collaço R.C.O., de Azevedo Calderon L., González W., José Rafael de Almeida, Marangoni S., Ramírez D., Resende L.M., Saulo L. Silva, Schezaro-Ramos R., Simioni L.R., Soares A.M.Fuentes:scopusEffect of a pool of peptides isolated from crotalus durissus terrificus (South American Rattlesnake) venom on glucose levels of mice fed on a high-fat diet
ArticleAbstract: This study investigated the effect of a pool of peptides, isolated from venom of Crotalus durissus tPalabras claves:Bioactive peptides, Crotalus durissus terrificus, glucose, hyperglycemia, Snake venomAutores:Alberício F., Marangoni S., Martins-Santos M.E.S., Oliveira E., Pinto F.C.H., Resende R.R., Saulo L. Silva, Soares A.M.Fuentes:scopus