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Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology(3)
Toxicon(3)
Current Pharmaceutical Biotechnology(1)
Drug Development Research(1)
International Journal of Biological Macromolecules(1)
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Farmacología y terapéutica(6)
Microorganismos, hongos y algas(6)
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Bioquímica(1)
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Harnessing snake venom phospholipases A <inf>2</inf> to novel approaches for overcoming antibiotic resistance
ReviewAbstract: The emergence of antibiotic resistance drives an essential race against time to reveal new molecularPalabras claves:antibacterial peptides, antibiotic-resistant bacteria, Peptidomimetics, Phospholipase A 2, Snake venomAutores:Antonio L.V. Palacios, Bruno Mendes, Gomes P.A.D.C., Jose Rafael de Almeida, Ricardo S.P. Patiño, Saulo L. Silva, Teixeira C.A.S.Fuentes:googleorcidscopusBothrops atrox from Ecuadorian Amazon: Initial analyses of venoms from individuals
ArticleAbstract: Bothrops atrox is the most clinically relevant snake species within the Amazon region, which includePalabras claves:antivenom, Enzymatic, Lethality, Phenotype, ToxicologicalAutores:Bruno Mendes, Carolina Proaño-Bolaños, David Salazar-Valenzuela, Evencio Joel Medina-Villamizar, Jose Rafael de Almeida, Ricardo S.P. Patiño, Saulo L. SilvaFuentes:googleorcidscopusCoaTx-II, a new dimeric Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles
ArticleAbstract: Snake venoms are rich and intriguing sources of biologically-active molecules that act on target celPalabras claves:Antibacterial effect, Crotalus oreganus abyssus, Lys49 phospholipase A 2, Myotoxicity, Snake venomAutores:de Azevedo Calderon L., González W., Jose Rafael de Almeida, Lancellotti M., Marangoni S., Ramírez D., Saulo L. Silva, Soares A.M.Fuentes:googleorcidscopusAnti-platelet aggregation activity of two novel acidic Asp49-phospholipases A<inf>2</inf> from Bothrops brazili snake venom
ArticleAbstract: Phospholipases A2 (PLA2s) are important enzymes present in snake venoms and are related to a wide spPalabras claves:Acidic phospholipases A 2, Anti-platelet aggregation activity, Bothrops brazili, Snake venomAutores:Alfonso J.J., Fuly A.L., Gómez A.F., Gomez M.C.V., Jose Rafael de Almeida, Kayano A.M., Moura L.A., Oliveira E., Saulo L. Silva, Simões-Silva R., Soares A.M., Sobrinho J.C., Souza V.R., Zanchi F.B., Zuliani J.P.Fuentes:googleorcidscopusAssessing the stability of historical and desiccated snake venoms from a medically important Ecuadorian collection
ArticleAbstract: Bothrops asper and Bothrops atrox are important venomous snakes from Ecuador responsible for the mosPalabras claves:Desiccated venom, Proteomic, Snake venom, stability, ToxicologicalAutores:Bruno Mendes, Caldeira C.A.S., Jose Rafael de Almeida, Laines J., LARES, Noroska Gabriela Salazar Mogollón, Pico J., Ricardo S.P. Patiño, Saulo L. Silva, Terán M.Fuentes:googleorcidscopusIn vitro effects of Crotalus atrox snake venom on chick and mouse neuromuscular preparations
ArticleAbstract: The neuromuscular effect of venoms is not a major clinical manifestation shared between rattlesnakesPalabras claves:Crotalus atrox, Myotoxicity, Neuromuscular blockade, Snake venomAutores:Bruno Mendes, Carregari V.C., Hyslop S., Jose Rafael de Almeida, Noroska Gabriela Salazar Mogollón, Pereira B.B., Santa Fé Miguel A.T., Saulo L. Silva, Schezaro-Ramos R.Fuentes:googleorcidscopusPotential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents
ArticleAbstract: Phospholipase A2 toxins present in snake venoms interact with biological membranes and serve as struPalabras claves:Leishmanicidal activity, Oligoarginine, peptide, PhospholipaseAutores:Bruno Mendes, Gadelha F.R., Gomes P.A.D.C., Jose Rafael de Almeida, Miguel D.C., Saulo L. Silva, Vale N.Fuentes:googleorcidscopusIsolation, structural and functional characterization of a new Lys49 phospholipase A<inf>2</inf> homologue from Bothrops neuwiedi urutu with bactericidal potential
ArticleAbstract: Snake venom is a complex mixture of active compounds consisting of 80-90% proteins and peptides thatPalabras claves:bactericidal activity, Bothrops neuwiedi, Phospholipase A 2, Snake venomAutores:Corrêa E.A., de Azevedo Calderon L., Diniz-Sousa R., Jose Rafael de Almeida, Kayano A.M., Marangoni S., Matos N.B., Resende L.M., Saulo L. Silva, Setúbal S.S., Soares A.M., Zanchi F.B., Zuliani J.P.Fuentes:googleorcidscopusSnake venom, a natural library of new potential therapeutic molecules: Challenges and current perspectives
ReviewAbstract: Background: Research involving snake venom has gradually surpassed the simple discovery of new molecPalabras claves:Biotechnological applications, New therapeutics, Protein purification, Snake venoms, Toxins, venomicsAutores:Alfonso J.J., Gómez A.F., Grabner F.P., Holanda R.J., Jose Rafael de Almeida, Kayano A.M., Moreira-Dill L.S., Saulo L. Silva, Simões-Silva R., Soares A.M., Sobrinho J.C., Stábeli R.G., Zaqueo K.D., Zuliani J.P.Fuentes:googleorcidscopus