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Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways
OtherAbstract: BACKGROUND AND PURPOSE The endogenous cannabinoid system participates in oligodendrocyte progenitorPalabras claves:Autores:Aminael Sánchez-RodríguezFuentes:googleFrom flamingo dance to (desirable) drug discovery: a nature-inspired approach
ReviewAbstract: The therapeutic effects of drugs are well known to result from their interaction with multiple intraPalabras claves:Autores:Aminael Sánchez-Rodríguez, Borges F., Eduardo Tejera, Mangiatordi G.F., Maykel Cruz-Monteagudo, Medina-Franco J.L., Natalia Dias Soeiro Cordeiro M., Nicolotti O., Schürer S.C., Yunierkis Perez-CastilloFuentes:googlescopusImproved virtual screening performance through docking scoring fusion in the discovery of dual target ligands for Parkinson’s disease
OtherAbstract: Virtual methodologies have become essential components of the drug discovery pipeline. Specifically,Palabras claves:Autores:Aminael Sánchez-Rodríguez, Cesar Paz-y-MiñoFuentes:googleMachine learning based multiclassifiers as a neurotoxicity estimation tool for ionic liquids
OtherAbstract: Ionic liquids (ILs) possess a unique physicochemical profile providing a wide range of applications.Palabras claves:Autores:Aminael Sánchez-Rodríguez, Cesar Paz-y-MiñoFuentes:googleLigand-Based Virtual Screening Using Tailored Ensembles: A Prioritization Tool for Dual A<inf>2A</inf> Adenosine Receptor Antagonists / Monoamine Oxidase B Inhibitors
ArticleAbstract: Background: Virtual Screening methodologies have emerged as efficient alternatives for the discoveryPalabras claves:A2A adenosine receptors antagonist, Dual-target drugs, Ensemble modeling, MAO-B inhibitors, QSAR, Virtual ScreeningAutores:Aminael Sánchez-Rodríguez, Ancede-Gallardo E., Borges F., Cagide F., Cesar Paz-y-Miño, Eduardo Tejera, Maykel Cruz-Monteagudo, Morales-Helguera A., Natalia Dias Soeiro Cordeiro M., Teijeira M., Yunierkis Perez-CastilloFuentes:googlescopusVirtual screening tailored ensembles of QSAR models for the discovery of dual A2A Adenosine Receptor Antagonists/Monoamine Oxidase B Inhibitors
OtherAbstract: Virtual Screening methodologies have emerged as efficient alternatives for the discovery of new drugPalabras claves:Autores:Aminael Sánchez-Rodríguez, Cesar Paz-y-MiñoFuentes:googleResidues of veterinary drugs: prevention of contamination in cattle farms
OtherAbstract: [Residues of veterinary drugs: prevention of contamination in cattle farms] FAO_logo AGRIS home-iconPalabras claves:Autores:Aminael Sánchez-RodríguezFuentes:googlePropiedades y efecto de los metabolitos secundarios sobre la prevención y reparacion de daños cutáneos
OtherAbstract: Incrementan la elasticidad del estrato córneo porque a su vez incrementan el ontenido de agua y porPalabras claves:Autores:Aminael Sánchez-RodríguezFuentes:googleSystemic QSAR and phenotypic virtual screening: chasing butterflies in drug discovery
ReviewAbstract: Current advances in systems biology suggest a new change of paradigm reinforcing the holistic naturePalabras claves:Autores:Aminael Sánchez-Rodríguez, Borges F., Eduardo Tejera, Maykel Cruz-Monteagudo, Medina-Franco J.L., Schürer S.C., Yunierkis Perez-CastilloFuentes:googlescopus